Holdings of iShares Biotechnology ETF
iShares Trust ·246 declared positions · as of Mar 31, 2026
Original filing · Net assets 8.1B $ · Ten largest lines: 47.4 % of the equity sleeve
Sector breakdown
- Health care 50.8 %
- Materials 1.7 %
- Industrials 1.1 %
- Unattributed 46.4 %
Titelia classification, company by company. The unattributed share stays visible.
Currency breakdown
- USD 100.0 %
The quoted currency of each line, as declared.
Country breakdown
- US 88.9 %
- NL 3.4 %
- DK 2.1 %
- BM 1.2 %
- CA 0.8 %
- DE 0.7 %
- IE 0.6 %
- FR 0.5 %
- CH 0.4 %
- KY 0.4 %
- SG 0.1 %
- JE 0.1 %
- Other countries 0.6 %
Shares computed on the equity sleeve.
| Rank | Country | Lines | Value | Share |
|---|---|---|---|---|
| 1 | US | 208 | 7.2B $ | 88.91 % |
| 2 | NL | 4 | 279.1M $ | 3.44 % |
| 3 | DK | 2 | 173.1M $ | 2.13 % |
| 4 | BM | 1 | 100.9M $ | 1.24 % |
| 5 | CA | 4 | 67.1M $ | 0.83 % |
| 6 | DE | 1 | 53.3M $ | 0.66 % |
| 7 | IE | 3 | 50.9M $ | 0.63 % |
| 8 | FR | 2 | 42M $ | 0.52 % |
| 9 | CH | 3 | 35.3M $ | 0.44 % |
| 10 | KY | 5 | 34.8M $ | 0.43 % |
| 11 | SG | 1 | 8.5M $ | 0.11 % |
| 12 | JE | 1 | 8.3M $ | 0.10 % |
Positions
| Rank | Company | Shares | Value | Weight |
|---|---|---|---|---|
| 1 | Gilead Sciences Inc | 4,515,707 | 629.4M $ | 7.75 % |
| 2 | Amgen Inc | 1,733,148 | 609.8M $ | 7.51 % |
| 3 | Vertex Pharmaceuticals Inc | 1,354,033 | 604.6M $ | 7.44 % |
| 4 | Regeneron Pharmaceuticals, Inc. | 758,232 | 585.8M $ | 7.21 % |
| 5 | Alnylam Pharmaceuticals Inc | 979,642 | 324.1M $ | 3.99 % |
| 6 | Insmed Inc | 1,587,887 | 259.7M $ | 3.20 % |
| 7 | Argenx SE | 341,883 | 249.7M $ | 3.07 % |
| 8 | Biogen Inc | 1,091,046 | 200M $ | 2.46 % |
| 9 | Natera Inc | 980,622 | 196.1M $ | 2.41 % |
| 10 | United Therapeutics Corp | 315,509 | 187.1M $ | 2.30 % |
| 11 | BEONE MEDICINES LTD | 529,143 | 157.1M $ | 1.93 % |
| 12 | Incyte Corp | 1,467,923 | 138.2M $ | 1.70 % |
| 13 | Moderna Inc | 2,692,459 | 136.8M $ | 1.68 % |
| 14 | Illumina Inc | 1,107,291 | 136.5M $ | 1.68 % |
| 15 | Revolution Medicines Inc | 1,283,912 | 124.9M $ | 1.54 % |
| 16 | Roivant Sciences Ltd | 3,642,557 | 100.9M $ | 1.24 % |
| 17 | Neurocrine Biosciences Inc | 727,502 | 95.8M $ | 1.18 % |
| 18 | Genmab A/S | 3,555,098 | 95.4M $ | 1.17 % |
| 19 | Bridgebio Pharma Inc | 1,238,687 | 92M $ | 1.13 % |
| 20 | Ionis Pharmaceuticals Inc | 1,205,549 | 90.5M $ | 1.11 % |
| 21 | Medpace Holdings Inc | 169,922 | 81.6M $ | 1.00 % |
| 22 | Madrigal Pharmaceuticals Inc | 155,341 | 81.3M $ | 1.00 % |
| 23 | Exelixis Inc | 1,871,326 | 80.3M $ | 0.99 % |
| 24 | BioMarin Pharmaceutical Inc | 1,412,330 | 79.8M $ | 0.98 % |
| 25 | Ascendis Pharma A/S | 339,948 | 77.8M $ | 0.96 % |
| 26 | Praxis Precision Medicines Inc | 195,097 | 62.9M $ | 0.77 % |
| 27 | Charles River Laboratories International Inc | 362,165 | 62.5M $ | 0.77 % |
| 28 | Arrowhead Pharmaceuticals Inc | 975,175 | 61.1M $ | 0.75 % |
| 29 | Vaxcyte Inc | 1,045,695 | 60.8M $ | 0.75 % |
| 30 | Bio-Techne Corp | 1,151,950 | 60.2M $ | 0.74 % |
| 31 | Cytokinetics Inc | 896,972 | 59.1M $ | 0.73 % |
| 32 | Halozyme Therapeutics Inc | 868,502 | 56.1M $ | 0.69 % |
| 33 | Axsome Therapeutics Inc | 319,088 | 53.9M $ | 0.66 % |
| 34 | BioNTech SE | 599,506 | 53.3M $ | 0.66 % |
| 35 | Krystal Biotech Inc | 188,966 | 48.8M $ | 0.60 % |
| 36 | Protagonist Therapeutics Inc | 447,047 | 47.1M $ | 0.58 % |
| 37 | Repligen Corp | 396,896 | 46.8M $ | 0.58 % |
| 38 | Kymera Therapeutics Inc | 521,385 | 43.4M $ | 0.53 % |
| 39 | Alkermes PLC | 1,216,662 | 43M $ | 0.53 % |
| 40 | Rhythm Pharmaceuticals Inc | 474,539 | 41.3M $ | 0.51 % |
| 41 | Abivax SA | 367,461 | 40.9M $ | 0.50 % |
| 42 | PTC Therapeutics Inc | 593,152 | 40.4M $ | 0.50 % |
| 43 | Cogent Biosciences Inc | 1,009,396 | 38.9M $ | 0.48 % |
| 44 | Arcellx Inc | 335,814 | 38.6M $ | 0.47 % |
| 45 | Terns Pharmaceuticals Inc | 713,848 | 37.6M $ | 0.46 % |
| 46 | Nuvalent Inc | 355,481 | 36.4M $ | 0.45 % |
| 47 | Mirum Pharmaceuticals Inc | 392,677 | 36.3M $ | 0.45 % |
| 48 | Tempus AI Inc | 773,906 | 35M $ | 0.43 % |
| 49 | Xenon Pharmaceuticals Inc | 598,390 | 34.8M $ | 0.43 % |
| 50 | Amicus Therapeutics Inc | 2,307,725 | 33.4M $ | 0.41 % |
| 51 | CRISPR Therapeutics AG | 663,733 | 31.6M $ | 0.39 % |
| 52 | Apellis Pharmaceuticals Inc | 778,245 | 31.3M $ | 0.39 % |
| 53 | Apogee Therapeutics Inc | 353,520 | 29.8M $ | 0.37 % |
| 54 | Scholar Rock Holding Corp | 593,730 | 29.2M $ | 0.36 % |
| 55 | ACADIA Pharmaceuticals Inc | 1,251,241 | 27.9M $ | 0.34 % |
| 56 | Bruker Corp | 764,342 | 27.6M $ | 0.34 % |
| 57 | Crinetics Pharmaceuticals Inc | 726,428 | 26.4M $ | 0.32 % |
| 58 | CG oncology Inc | 379,295 | 25.7M $ | 0.32 % |
| 59 | Spyre Therapeutics Inc | 478,909 | 24.2M $ | 0.30 % |
| 60 | Erasca Inc | 1,384,399 | 22.4M $ | 0.28 % |
| 61 | Tarsus Pharmaceuticals Inc | 297,522 | 20.9M $ | 0.26 % |
| 62 | Twist Bioscience Corp | 436,795 | 20.8M $ | 0.26 % |
| 63 | CENTESSA PHARMACEUTICALS PLC | 520,762 | 20.7M $ | 0.25 % |
| 64 | Ideaya Biosciences Inc | 615,636 | 20.5M $ | 0.25 % |
| 65 | Denali Therapeutics Inc | 1,055,210 | 20.3M $ | 0.25 % |
| 66 | Travere Therapeutics Inc | 674,600 | 20M $ | 0.25 % |
| 67 | ImmunityBio Inc | 2,572,701 | 19.7M $ | 0.24 % |
| 68 | Arcutis Biotherapeutics Inc | 814,779 | 19.2M $ | 0.24 % |
| 69 | Veracyte Inc | 579,343 | 18.7M $ | 0.23 % |
| 70 | Structure Therapeutics Inc | 381,676 | 18.4M $ | 0.23 % |
| 71 | Edgewise Therapeutics Inc | 572,192 | 18M $ | 0.22 % |
| 72 | 10X Genomics Inc | 841,716 | 17.9M $ | 0.22 % |
| 73 | LEGEND BIOTECH CORP | 983,928 | 17.8M $ | 0.22 % |
| 74 | Newamsterdam Pharma Co NV | 537,784 | 17.2M $ | 0.21 % |
| 75 | Vera Therapeutics Inc | 419,778 | 16.9M $ | 0.21 % |
| 76 | Dyne Therapeutics Inc | 917,470 | 16.6M $ | 0.20 % |
| 77 | Beam Therapeutics Inc | 692,124 | 16.5M $ | 0.20 % |
| 78 | BioCryst Pharmaceuticals Inc | 1,715,826 | 16.3M $ | 0.20 % |
| 79 | Kodiak Sciences Inc | 422,431 | 16.1M $ | 0.20 % |
| 80 | Sarepta Therapeutics Inc | 739,607 | 16.1M $ | 0.20 % |
| 81 | Caris Life Sciences Inc | 898,011 | 16.1M $ | 0.20 % |
| 82 | Immunovant Inc | 626,211 | 15.6M $ | 0.19 % |
| 83 | ADMA Biologics Inc | 1,711,239 | 15.4M $ | 0.19 % |
| 84 | Adaptive Biotechnologies Corp | 1,105,997 | 15.4M $ | 0.19 % |
| 85 | Summit Therapeutics Inc | 799,477 | 15.2M $ | 0.19 % |
| 86 | Oruka Therapeutics Inc | 304,331 | 14.9M $ | 0.18 % |
| 87 | Syndax Pharmaceuticals Inc | 631,524 | 14.8M $ | 0.18 % |
| 88 | Tango Therapeutics Inc | 687,885 | 14.4M $ | 0.18 % |
| 89 | Ultragenyx Pharmaceutical Inc | 680,286 | 14.3M $ | 0.18 % |
| 90 | Disc Medicine Inc | 214,889 | 13.7M $ | 0.17 % |
| 91 | Agios Pharmaceuticals Inc | 400,087 | 13.5M $ | 0.17 % |
| 92 | GRAIL Inc | 261,045 | 13.5M $ | 0.17 % |
| 93 | Definium Therapeutics Inc | 703,030 | 13.3M $ | 0.16 % |
| 94 | Zymeworks Inc | 529,981 | 13.3M $ | 0.16 % |
| 95 | Arcus Biosciences Inc | 612,355 | 13.2M $ | 0.16 % |
| 96 | Aurinia Pharmaceuticals Inc | 874,336 | 13M $ | 0.16 % |
| 97 | Enliven Therapeutics Inc | 322,556 | 12.6M $ | 0.16 % |
| 98 | Day One Biopharmaceuticals Inc | 578,773 | 12.4M $ | 0.15 % |
| 99 | Vericel Corp | 373,502 | 12M $ | 0.15 % |
| 100 | Mineralys Therapeutics Inc | 439,648 | 11.9M $ | 0.15 % |