Holdings of Direxion Daily S&P Biotech Bull 3X Shares
Direxion Shares ETF Trust ·145 declared positions · as of Apr 30, 2026
Original filing · Net assets 518.9M $ · Ten largest lines: 14.8 % of the equity sleeve
Sector breakdown
- Health care 11.8 %
- Materials 1.1 %
- Industrials 1.1 %
- Unattributed 85.9 %
Titelia classification, company by company. The unattributed share stays visible.
Currency breakdown
- USD 100.0 %
The quoted currency of each line, as declared.
Country breakdown
- US 95.2 %
- IE 1.5 %
- CH 1.2 %
- BM 1.1 %
- VG 0.5 %
- NL 0.5 %
Shares computed on the equity sleeve.
| Rank | Country | Lines | Value | Share |
|---|---|---|---|---|
| 1 | US | 139 | 406.1M $ | 95.23 % |
| 2 | IE | 2 | 6.5M $ | 1.53 % |
| 3 | CH | 1 | 5.1M $ | 1.19 % |
| 4 | BM | 1 | 4.7M $ | 1.10 % |
| 5 | VG | 1 | 2.1M $ | 0.50 % |
| 6 | NL | 1 | 1.9M $ | 0.45 % |
Positions
| Rank | Company | Shares | Value | Weight |
|---|---|---|---|---|
| 1 | Apellis Pharmaceuticals Inc | 194,250 | 8M $ | 1.53 % |
| 2 | Revolution Medicines Inc | 48,748 | 7M $ | 1.35 % |
| 3 | Travere Therapeutics Inc | 164,067 | 6.9M $ | 1.33 % |
| 4 | Arrowhead Pharmaceuticals Inc | 83,558 | 6.1M $ | 1.18 % |
| 5 | Twist Bioscience Corp | 103,603 | 6.1M $ | 1.17 % |
| 6 | Summit Therapeutics Inc | 278,847 | 6M $ | 1.15 % |
| 7 | Alkermes PLC | 174,823 | 5.9M $ | 1.14 % |
| 8 | TG Therapeutics Inc | 173,080 | 5.8M $ | 1.13 % |
| 9 | Madrigal Pharmaceuticals Inc | 11,249 | 5.8M $ | 1.12 % |
| 10 | Beam Therapeutics Inc | 186,154 | 5.6M $ | 1.09 % |
| 11 | Apogee Therapeutics Inc | 65,006 | 5.4M $ | 1.04 % |
| 12 | Scholar Rock Holding Corp | 112,425 | 5.2M $ | 1.01 % |
| 13 | Praxis Precision Medicines Inc | 16,345 | 5.2M $ | 1.00 % |
| 14 | Exelixis Inc | 116,281 | 5.2M $ | 1.00 % |
| 15 | Mirum Pharmaceuticals Inc | 52,917 | 5.1M $ | 0.99 % |
| 16 | United Therapeutics Corp | 8,914 | 5.1M $ | 0.98 % |
| 17 | Natera Inc | 24,696 | 5.1M $ | 0.98 % |
| 18 | Celcuity Inc | 41,941 | 5.1M $ | 0.98 % |
| 19 | CRISPR Therapeutics AG | 97,235 | 5.1M $ | 0.98 % |
| 20 | Krystal Biotech Inc | 19,037 | 5M $ | 0.96 % |
| 21 | Protagonist Therapeutics Inc | 50,321 | 5M $ | 0.96 % |
| 22 | Neurocrine Biosciences Inc | 37,476 | 4.9M $ | 0.95 % |
| 23 | Incyte Corp | 51,287 | 4.9M $ | 0.94 % |
| 24 | CG oncology Inc | 73,170 | 4.9M $ | 0.94 % |
| 25 | Cytokinetics Inc | 76,297 | 4.9M $ | 0.94 % |
| 26 | Nuvalent Inc | 48,521 | 4.9M $ | 0.94 % |
| 27 | Ionis Pharmaceuticals Inc | 64,911 | 4.9M $ | 0.94 % |
| 28 | Bridgebio Pharma Inc | 68,003 | 4.8M $ | 0.93 % |
| 29 | Vaxcyte Inc | 84,388 | 4.8M $ | 0.93 % |
| 30 | Kymera Therapeutics Inc | 59,553 | 4.8M $ | 0.93 % |
| 31 | Biogen Inc | 25,484 | 4.8M $ | 0.93 % |
| 32 | Cogent Biosciences Inc | 134,554 | 4.8M $ | 0.93 % |
| 33 | PTC Therapeutics Inc | 73,928 | 4.8M $ | 0.93 % |
| 34 | Insmed Inc | 34,830 | 4.7M $ | 0.92 % |
| 35 | Alnylam Pharmaceuticals Inc | 15,151 | 4.7M $ | 0.90 % |
| 36 | Roivant Sciences Ltd | 164,121 | 4.7M $ | 0.90 % |
| 37 | Halozyme Therapeutics Inc | 73,023 | 4.6M $ | 0.90 % |
| 38 | Arcutis Biotherapeutics Inc | 196,991 | 4.6M $ | 0.88 % |
| 39 | Spyre Therapeutics Inc | 61,270 | 4.6M $ | 0.88 % |
| 40 | Soleno Therapeutics Inc | 85,699 | 4.5M $ | 0.87 % |
| 41 | AbbVie Inc | 21,322 | 4.5M $ | 0.87 % |
| 42 | Amgen Inc | 12,853 | 4.5M $ | 0.86 % |
| 43 | Regeneron Pharmaceuticals, Inc. | 6,267 | 4.4M $ | 0.85 % |
| 44 | Ultragenyx Pharmaceutical Inc | 178,057 | 4.4M $ | 0.85 % |
| 45 | ACADIA Pharmaceuticals Inc | 195,542 | 4.4M $ | 0.85 % |
| 46 | Rhythm Pharmaceuticals Inc | 53,930 | 4.4M $ | 0.85 % |
| 47 | Gilead Sciences Inc | 33,255 | 4.4M $ | 0.84 % |
| 48 | BioMarin Pharmaceutical Inc | 80,485 | 4.3M $ | 0.84 % |
| 49 | Viking Therapeutics Inc | 135,757 | 4.2M $ | 0.82 % |
| 50 | Vertex Pharmaceuticals Inc | 9,860 | 4.2M $ | 0.81 % |
| 51 | ImmunityBio Inc | 587,041 | 4.2M $ | 0.80 % |
| 52 | Immunovant Inc | 147,047 | 4M $ | 0.77 % |
| 53 | Moderna Inc | 86,741 | 4M $ | 0.77 % |
| 54 | Vera Therapeutics Inc | 109,557 | 3.9M $ | 0.75 % |
| 55 | Immunome Inc | 168,145 | 3.9M $ | 0.74 % |
| 56 | Disc Medicine Inc | 57,978 | 3.8M $ | 0.74 % |
| 57 | Veracyte Inc | 112,171 | 3.7M $ | 0.71 % |
| 58 | Sarepta Therapeutics Inc | 175,121 | 3.7M $ | 0.70 % |
| 59 | Catalyst Pharmaceuticals Inc | 129,949 | 3.7M $ | 0.70 % |
| 60 | BioCryst Pharmaceuticals Inc | 381,305 | 3.5M $ | 0.67 % |
| 61 | Dyne Therapeutics Inc | 196,941 | 3.5M $ | 0.67 % |
| 62 | Kodiak Sciences Inc | 76,962 | 3.3M $ | 0.64 % |
| 63 | Recursion Pharmaceuticals Inc | 958,574 | 3.3M $ | 0.64 % |
| 64 | GRAIL Inc | 59,651 | 3.2M $ | 0.63 % |
| 65 | Arcus Biosciences Inc | 123,926 | 3.2M $ | 0.61 % |
| 66 | Agios Pharmaceuticals Inc | 110,585 | 3.1M $ | 0.60 % |
| 67 | Denali Therapeutics Inc | 162,191 | 3M $ | 0.59 % |
| 68 | Oruka Therapeutics Inc | 43,576 | 3M $ | 0.57 % |
| 69 | Dianthus Therapeutics Inc | 33,605 | 3M $ | 0.57 % |
| 70 | Intellia Therapeutics Inc | 215,007 | 2.9M $ | 0.56 % |
| 71 | Erasca Inc | 271,194 | 2.9M $ | 0.56 % |
| 72 | ADMA Biologics Inc | 281,674 | 2.9M $ | 0.56 % |
| 73 | Syndax Pharmaceuticals Inc | 134,242 | 2.9M $ | 0.55 % |
| 74 | Ardelyx Inc | 438,991 | 2.8M $ | 0.54 % |
| 75 | Ideaya Biosciences Inc | 93,300 | 2.7M $ | 0.52 % |
| 76 | Mineralys Therapeutics Inc | 101,556 | 2.7M $ | 0.52 % |
| 77 | Nurix Therapeutics Inc | 160,937 | 2.7M $ | 0.52 % |
| 78 | Tango Therapeutics Inc | 112,975 | 2.4M $ | 0.47 % |
| 79 | Celldex Therapeutics Inc | 70,017 | 2.3M $ | 0.44 % |
| 80 | Capricor Therapeutics Inc | 67,108 | 2.3M $ | 0.43 % |
| 81 | Vericel Corp | 63,931 | 2.2M $ | 0.43 % |
| 82 | Inhibrx Biosciences Inc | 16,961 | 2.2M $ | 0.42 % |
| 83 | Monte Rosa Therapeutics Inc | 112,609 | 2.2M $ | 0.42 % |
| 84 | Novavax Inc | 267,379 | 2.1M $ | 0.41 % |
| 85 | Biohaven Ltd | 220,160 | 2.1M $ | 0.41 % |
| 86 | Stoke Therapeutics Inc | 64,471 | 2.1M $ | 0.41 % |
| 87 | Relay Therapeutics Inc | 162,116 | 2.1M $ | 0.40 % |
| 88 | Taysha Gene Therapies Inc | 322,791 | 2.1M $ | 0.40 % |
| 89 | Viridian Therapeutics Inc | 152,815 | 2.1M $ | 0.40 % |
| 90 | Olema Pharmaceuticals Inc | 141,558 | 2M $ | 0.39 % |
| 91 | Palvella Therapeutics Inc | 15,705 | 2M $ | 0.39 % |
| 92 | uniQure NV | 97,163 | 1.9M $ | 0.37 % |
| 93 | AnaptysBio Inc | 29,328 | 1.9M $ | 0.37 % |
| 94 | Corvus Pharmaceuticals Inc | 121,201 | 1.8M $ | 0.35 % |
| 95 | MannKind Corp | 625,921 | 1.8M $ | 0.34 % |
| 96 | CareDx Inc | 84,742 | 1.8M $ | 0.34 % |
| 97 | KalVista Pharmaceuticals Inc | 61,671 | 1.6M $ | 0.32 % |
| 98 | Iovance Biotherapeutics Inc | 466,051 | 1.6M $ | 0.30 % |
| 99 | Vir Biotechnology Inc | 144,675 | 1.5M $ | 0.28 % |
| 100 | Geron Corp | 951,040 | 1.5M $ | 0.28 % |