| 1 | Nuvalent Inc | 17,248,450 | 1.8B $ | |
| 2 | Cogent Biosciences Inc | 9,043,903 | 348.1M $ | |
| 3 | Praxis Precision Medicines Inc | 963,351 | 310.4M $ | |
| 4 | Viatris Inc | 20,206,170 | 273M $ | |
| 5 | United Therapeutics Corp | 457,000 | 271M $ | |
| 6 | Revolution Medicines Inc | 2,297,000 | 223.4M $ | |
| 7 | Celcuity Inc | 1,714,000 | 195.6M $ | |
| 8 | Centene Corp | 5,917,091 | 193.7M $ | |
| 9 | Larimar Therapeutics Inc | 35,606,974 | 160.2M $ | |
| 10 | Brookdale Senior Living Inc | 11,637,032 | 159.2M $ | |
| 11 | Vera Therapeutics Inc | 3,722,100 | 149.7M $ | |
| 12 | Ionis Pharmaceuticals Inc | 1,979,669 | 148.7M $ | |
| 13 | BioCryst Pharmaceuticals Inc | 15,038,000 | 143.2M $ | |
| 14 | Inspire Medical Systems Inc | 2,703,238 | 139.4M $ | |
| 15 | LEGEND BIOTECH CORP | 7,687,638 | 139.1M $ | |
| 16 | AdaptHealth Corp | 11,477,730 | 136.6M $ | |
| 17 | Acadia Healthcare Co Inc | 4,520,000 | 105.7M $ | |
| 18 | Arrowhead Pharmaceuticals Inc | 1,573,297 | 98.6M $ | |
| 19 | Catalyst Pharmaceuticals Inc | 3,943,600 | 97.6M $ | |
| 20 | Indivior Pharmaceuticals Inc | 3,097,790 | 94.4M $ | |
| 21 | Syndax Pharmaceuticals Inc | 3,779,900 | 88.3M $ | |
| 22 | Tango Therapeutics Inc | 4,146,813 | 86.8M $ | |
| 23 | Dianthus Therapeutics Inc | 1,019,813 | 85.6M $ | |
| 24 | Pfizer Inc | 3,040,000 | 85.4M $ | |
| 25 | Neurocrine Biosciences Inc | 610,000 | 80.4M $ | |
| 26 | Day One Biopharmaceuticals Inc | 3,723,131 | 79.8M $ | |
| 27 | Savara Inc | 13,569,000 | 74.1M $ | |
| 28 | Enhabit Inc | 4,747,746 | 66.9M $ | |
| 29 | Genmab A/S | 2,462,000 | 66.1M $ | |
| 30 | Bio-Rad Laboratories Inc | 226,070 | 63M $ | |
| 31 | Lantheus Holdings Inc | 827,999 | 62.8M $ | |
| 32 | ARS Pharmaceuticals Inc | 7,503,812 | 60.3M $ | |
| 33 | Stoke Therapeutics Inc | 1,823,500 | 59.4M $ | |
| 34 | Envista Holdings Corp | 2,210,100 | 56.1M $ | |
| 35 | Ideaya Biosciences Inc | 1,530,008 | 51M $ | |
| 36 | Belite Bio Inc | 304,013 | 48.5M $ | |
| 37 | BioMarin Pharmaceutical Inc | 851,556 | 48.1M $ | |
| 38 | Kymera Therapeutics Inc | 561,170 | 46.7M $ | |
| 39 | Certara Inc | 7,808,605 | 44.5M $ | |
| 40 | BridgeBio Oncology Therapeutics Inc | 4,885,446 | 43.7M $ | |
| 41 | Disc Medicine Inc | 657,000 | 42M $ | |
| 42 | Sionna Therapeutics Inc | 970,590 | 38.9M $ | |
| 43 | CareDx Inc | 2,191,000 | 38M $ | |
| 44 | Structure Therapeutics Inc | 767,993 | 37M $ | |
| 45 | Veracyte Inc | 726,000 | 23.4M $ | |
| 46 | Alnylam Pharmaceuticals Inc | 67,935 | 22.5M $ | |
| 47 | Embecta Corp | 2,534,961 | 22.4M $ | |
| 48 | Tyra Biosciences Inc | 549,000 | 21M $ | |
| 49 | Foghorn Therapeutics Inc | 4,394,367 | 21M $ | |
| 50 | Compass Therapeutics Inc | 3,606,000 | 19.1M $ | |
| 51 | Monopar Therapeutics Inc | 323,745 | 17.7M $ | |
| 52 | Kyverna Therapeutics Inc | 2,000,000 | 17.3M $ | |
| 53 | SpyGlass Pharma Inc | 550,000 | 14.3M $ | |
| 54 | Beta Bionics Inc | 1,324,000 | 13.3M $ | |
| 55 | Taysha Gene Therapies Inc | 2,722,165 | 12.2M $ | |
| 56 | Oncology Institute Inc/The | 3,360,052 | 10.3M $ | |
| 57 | Cullinan Therapeutics Inc | 386,169 | 5.5M $ | |
| 58 | Annexon Inc | 583,913 | 3.2M $ | |
| 59 | Alector Inc | 1,055,192 | 2.3M $ | |
| 60 | Edwards Lifesciences Corp | 13,702 | 1.1M $ | |
| 61 | VeraDermics Inc | 5,000 | 315.8K $ | |
| 62 | Humana Inc | 917 | 159K $ | |
| 63 | PMV Pharmaceuticals Inc | 8,790 | 10.9K $ | |
| 64 | Myriad Genetics Inc | 505 | 2.3K $ | |