Titelia

Holdings of SPHERA FUNDS MANAGEMENT LTD.

76 declared positions · as of Mar 31, 2026

Original filing · Ten largest lines: 41.2 % of the equity sleeve

Sector breakdown

  • Health care 18.5 %
  • Technology 1.9 %
  • Consumer discretionary 1.5 %
  • Unattributed 78.2 %

Titelia classification, company by company. The unattributed share stays visible.

Currency breakdown

  • USD 100.0 %

The quoted currency of each line, as declared.

Country breakdown

  • US 86.5 %
  • IL 7.7 %
  • FR 2.9 %
  • GB 1.5 %
  • DK 1.4 %

Shares computed on the equity sleeve.

CountryLinesValueShare
US70390.7M $86.53 %
IL234.9M $7.72 %
FR113M $2.88 %
GB16.7M $1.49 %
DK26.3M $1.39 %

Positions

CompanySharesValueWeight
Mineralys Therapeutics Inc 1,339,97136.3M $
Teva Pharmaceutical Industries Ltd 1,136,97534.2M $
Bridgebio Pharma Inc 245,24618.2M $
Biogen Inc 92,52617M $
Ultragenyx Pharmaceutical Inc 809,33317M $
Syndax Pharmaceuticals Inc 724,56316.9M $
Cogent Biosciences Inc 416,34016M $
Sanofi SA 269,51513M $
Amicus Therapeutics Inc 603,3778.7M $
Apellis Pharmaceuticals Inc 214,9148.6M $
Palo Alto Networks Inc 52,8008.5M $
Eli Lilly & Co 9,0408.3M $
BioCryst Pharmaceuticals Inc 866,4648.2M $
BioMarin Pharmaceutical Inc 139,9007.9M $
Celldex Therapeutics Inc 243,5757.7M $
Ormat Technologies Inc 68,2507.6M $
Soleno Therapeutics Inc 216,2817.2M $
Tango Therapeutics Inc 343,5637.2M $
Johnson & Johnson 28,8317M $
Trevi Therapeutics Inc 574,0296.8M $
ORIC Pharmaceuticals Inc 537,6286.8M $
Maze Therapeutics Inc 227,3436.8M $
GSK PLC 122,0006.7M $
Amazon.com Inc 31,9406.7M $
AbbVie Inc 30,2566.6M $
Applied Optoelectronics Inc 73,4006.2M $
Enliven Therapeutics Inc 153,2656M $
Merck & Co Inc 48,6005.8M $
Vor BioPharma Inc 321,9175.7M $
ACADIA Pharmaceuticals Inc 256,2025.7M $
Novartis AG 37,0005.7M $
Eledon Pharmaceuticals Inc 1,772,1315.5M $
Enphase Energy Inc 142,4195.4M $
Revolution Medicines Inc 55,1105.4M $
Pfizer Inc 186,0005.2M $
Forte Biosciences Inc 184,9844.8M $
Madrigal Pharmaceuticals Inc 9,0404.7M $
Scholar Rock Holding Corp 94,2654.6M $
Novo Nordisk A/S 120,6774.4M $
Kodiak Sciences Inc 114,7964.4M $
ZENAS BIOPHARMA INC 214,3344.2M $
Relay Therapeutics Inc 408,4364.1M $
Savara Inc 739,1644M $
Corvus Pharmaceuticals Inc 247,9613.6M $
Ovid therapeutics Inc 1,622,8283.6M $
Disc Medicine Inc 53,5383.4M $
Upstream Bio Inc 358,0003.2M $
Palisade Bio Inc 1,733,4713M $
Dyne Therapeutics Inc 160,5942.9M $
Climb Bio Inc 419,2472.9M $
SolarEdge Technologies Inc 52,8362.7M $
Amgen Inc 7,5002.6M $
Cytokinetics Inc 39,8172.6M $
Structure Therapeutics Inc 50,8002.4M $
Kura Oncology Inc 295,5222.4M $
Generate Biomedicines Inc 185,0002.3M $
iShares Bitcoin Trust ETF 59,5052.3M $
Contineum Therapeutics Inc 173,4752.3M $
Tenax Therapeutics Inc 136,0152.2M $
Prelude Therapeutics Inc 558,3391.9M $
Ascendis Pharma A/S 8,0001.8M $
Verastem Inc 343,6781.8M $
Voyager Therapeutics Inc 469,7611.8M $
Shattuck Labs Inc 280,7861.8M $
Evommune Inc 78,2341.8M $
BioAge Labs Inc 86,5181.5M $
Organogenesis Holdings Inc 550,0001.3M $
CURIS INC 1,994,9371.1M $
Bristol-Myers Squibb Co 17,5001.1M $
CytomX Therapeutics Inc 220,0001M $
Nice Ltd 5,611618.7K $
WEREWOLF THERAPEUTICS INC 626,810521.9K $
SKYE BIOSCIENCE INC 678,928417.3K $
Precision BioSciences Inc 40,000220K $
APREA THERAPEUTICS INC 270,000206K $
Foghorn Therapeutics Inc 12,22458.4K $