| 1 | Scholar Rock Holding Corp | 10,825,013 | 532.2M $ | |
| 2 | Kymera Therapeutics Inc | 3,186,830 | 265.4M $ | |
| 3 | Erasca Inc | 11,244,246 | 181.9M $ | |
| 4 | Edgewise Therapeutics Inc | 4,430,263 | 139.6M $ | |
| 5 | BEONE MEDICINES LTD | 465,000 | 138.1M $ | |
| 6 | Tango Therapeutics Inc | 5,657,105 | 118.3M $ | |
| 7 | Bicara Therapeutics Inc | 5,802,970 | 115.4M $ | |
| 8 | Revolution Medicines Inc | 1,110,980 | 108M $ | |
| 9 | Arrowhead Pharmaceuticals Inc | 1,615,476 | 101.3M $ | |
| 10 | VeraDermics Inc | 1,505,374 | 95.1M $ | |
| 11 | Olema Pharmaceuticals Inc | 4,756,949 | 70.9M $ | |
| 12 | Crinetics Pharmaceuticals Inc | 1,903,636 | 69.1M $ | |
| 13 | LEXICON PHARMACEUTICALS INC | 44,303,518 | 69.1M $ | |
| 14 | Cogent Biosciences Inc | 1,709,279 | 65.8M $ | |
| 15 | Stoke Therapeutics Inc | 1,995,347 | 65M $ | |
| 16 | Arcus Biosciences Inc | 3,007,077 | 65M $ | |
| 17 | Structure Therapeutics Inc | 1,328,698 | 64M $ | |
| 18 | Disc Medicine Inc | 988,401 | 63.2M $ | |
| 19 | Rhythm Pharmaceuticals Inc | 725,511 | 63.1M $ | |
| 20 | Solid Biosciences Inc | 7,690,405 | 55.4M $ | |
| 21 | Septerna Inc | 2,000,000 | 48.1M $ | |
| 22 | CENTESSA PHARMACEUTICALS PLC | 1,053,464 | 41.8M $ | |
| 23 | Spyre Therapeutics Inc | 818,598 | 41.3M $ | |
| 24 | Cytokinetics Inc | 613,952 | 40.5M $ | |
| 25 | Dyne Therapeutics Inc | 2,229,125 | 40.4M $ | |
| 26 | Taysha Gene Therapies Inc | 8,829,913 | 39.5M $ | |
| 27 | DBV Technologies SA | 1,857,362 | 38.8M $ | |
| 28 | ORIC Pharmaceuticals Inc | 2,998,192 | 38M $ | |
| 29 | Palvella Therapeutics Inc | 257,485 | 32.1M $ | |
| 30 | Enliven Therapeutics Inc | 746,226 | 29.3M $ | |
| 31 | Denali Therapeutics Inc | 1,396,513 | 26.8M $ | |
| 32 | Remitly Global Inc | 1,543,271 | 24.2M $ | |
| 33 | DAMORA THERAPEUTICS INC | 900,000 | 23.3M $ | |
| 34 | Annexon Inc | 3,958,646 | 21.9M $ | |
| 35 | Trevi Therapeutics Inc | 1,786,867 | 21.3M $ | |
| 36 | Rapport Therapeutics Inc | 641,469 | 20.1M $ | |
| 37 | Alphabet Inc | 65,703 | 18.9M $ | |
| 38 | Fulcrum Therapeutics Inc | 2,350,000 | 18M $ | |
| 39 | Amylyx Pharmaceuticals Inc | 1,230,000 | 17.1M $ | |
| 40 | Cullinan Therapeutics Inc | 1,193,410 | 17M $ | |
| 41 | Neumora Therapeutics Inc | 8,497,822 | 16.6M $ | |
| 42 | CytomX Therapeutics Inc | 3,457,711 | 16.3M $ | |
| 43 | NVIDIA Corp | 89,085 | 15.5M $ | |
| 44 | Silence Therapeutics PLC | 2,911,438 | 15.3M $ | |
| 45 | Microsoft Corp | 41,380 | 15.3M $ | |
| 46 | Monopar Therapeutics Inc | 270,118 | 14.8M $ | |
| 47 | Taiwan Semiconductor Manufacturing Co Ltd | 42,200 | 14.3M $ | |
| 48 | Sionna Therapeutics Inc | 300,000 | 12M $ | |
| 49 | Rezolute Inc | 3,328,287 | 10.2M $ | |
| 50 | Inhibikase Therapeutics Inc | 5,850,000 | 9.8M $ | |
| 51 | Amazon.com Inc | 46,641 | 9.7M $ | |
| 52 | Generate Biomedicines Inc | 736,104 | 9.2M $ | |
| 53 | MapLight Therapeutics Inc | 450,000 | 9.1M $ | |
| 54 | ServiceNow Inc | 87,090 | 9.1M $ | |
| 55 | Crowdstrike Holdings Inc | 23,070 | 9M $ | |
| 56 | PDD Holdings Inc | 83,401 | 8.5M $ | |
| 57 | Tesla Inc | 21,500 | 8M $ | |
| 58 | NovaBridge Biosciences | 3,000,000 | 7.4M $ | |
| 59 | Bicycle Therapeutics PLC | 1,560,882 | 7.2M $ | |
| 60 | Aadi Bioscience Inc | 2,082,000 | 7.2M $ | |
| 61 | Tenax Therapeutics Inc | 427,141 | 6.8M $ | |
| 62 | VTV THERAPEUTICS INC | 163,000 | 6.5M $ | |
| 63 | Datadog Inc | 54,300 | 6.4M $ | |
| 64 | Dynatrace Inc | 150,000 | 5.5M $ | |
| 65 | Workiva Inc | 92,500 | 5.5M $ | |
| 66 | Absci Corp | 1,800,000 | 5.4M $ | |
| 67 | Invivyd Inc | 4,000,000 | 5.2M $ | |
| 68 | IonQ Inc | 170,000 | 4.9M $ | |
| 69 | Broadcom Inc | 15,000 | 4.6M $ | |
| 70 | AGOMAB THERAPEUTICS SA | 411,250 | 4.3M $ | |
| 71 | Seer Inc | 2,458,673 | 4.1M $ | |
| 72 | Korro Bio Inc | 347,718 | 3.9M $ | |
| 73 | Agenus Inc | 1,064,250 | 3.6M $ | |
| 74 | Foghorn Therapeutics Inc | 720,720 | 3.4M $ | |
| 75 | Forgent Power Solutions Inc | 100,000 | 2.9M $ | |
| 76 | KALARIS THERAPEUTICS INC | 435,798 | 2.5M $ | |
| 77 | Gitlab Inc | 100,000 | 2.2M $ | |
| 78 | Micron Technology Inc | 6,000 | 2M $ | |
| 79 | Gossamer Bio Inc | 5,208,968 | 1.7M $ | |
| 80 | KE Holdings Inc | 100,000 | 1.5M $ | |
| 81 | Rani Therapeutics Holdings Inc | 2,000,000 | 1.5M $ | |
| 82 | Aeva Technologies Inc | 110,000 | 1.4M $ | |
| 83 | Medline Inc | 25,000 | 1.1M $ | |
| 84 | Figma Inc | 50,000 | 1.1M $ | |
| 85 | Primo Brands Corp | 50,000 | 941.5K $ | |