| 1 | Krystal Biotech Inc | 1 153 087 | 297,9 M $ | |
| 2 | Celcuity Inc | 1 284 378 | 146,6 M $ | |
| 3 | TG Therapeutics Inc | 4 029 319 | 133,9 M $ | |
| 4 | Insulet Corp | 562 500 | 118 M $ | |
| 5 | United Therapeutics Corp | 187 187 | 111 M $ | |
| 6 | Praxis Precision Medicines Inc | 330 517 | 106,5 M $ | |
| 7 | Vericel Corp | 2 549 079 | 82 M $ | |
| 8 | ANI Pharmaceuticals Inc | 820 243 | 63,1 M $ | |
| 9 | Globus Medical Inc | 729 467 | 62,9 M $ | |
| 10 | Geron Corp | 41 508 659 | 61,8 M $ | |
| 11 | Twist Bioscience Corp | 1 226 629 | 58,3 M $ | |
| 12 | Edgewise Therapeutics Inc | 1 449 915 | 45,7 M $ | |
| 13 | Beta Bionics Inc | 4 354 501 | 43,6 M $ | |
| 14 | Alnylam Pharmaceuticals Inc | 131 650 | 43,6 M $ | |
| 15 | Syndax Pharmaceuticals Inc | 1 726 908 | 40,3 M $ | |
| 16 | Indivior Pharmaceuticals Inc | 1 274 000 | 38,8 M $ | |
| 17 | NeuroPace Inc | 2 932 207 | 38,6 M $ | |
| 18 | Mirum Pharmaceuticals Inc | 400 306 | 37 M $ | |
| 19 | BioMarin Pharmaceutical Inc | 650 572 | 36,8 M $ | |
| 20 | Progyny Inc | 2 067 000 | 35,1 M $ | |
| 21 | Inspire Medical Systems Inc | 576 299 | 29,7 M $ | |
| 22 | Edap Tms SA | 7 309 254 | 27,2 M $ | |
| 23 | Merck & Co Inc | 203 000 | 24,4 M $ | |
| 24 | Organogenesis Holdings Inc | 10 085 951 | 23,9 M $ | |
| 25 | Natera Inc | 119 000 | 23,8 M $ | |
| 26 | Axogen Inc | 679 170 | 22,5 M $ | |
| 27 | Vaxcyte Inc | 385 472 | 22,4 M $ | |
| 28 | Cerus Corp | 10 753 700 | 19,6 M $ | |
| 29 | Trevi Therapeutics Inc | 1 620 000 | 19,3 M $ | |
| 30 | Inhibikase Therapeutics Inc | 10 875 000 | 18,3 M $ | |
| 31 | Context Therapeutics Inc | 6 963 141 | 18,2 M $ | |
| 32 | Vir Biotechnology Inc | 2 002 000 | 17,9 M $ | |
| 33 | Travere Therapeutics Inc | 546 000 | 16,2 M $ | |
| 34 | Tandem Diabetes Care Inc | 783 000 | 15 M $ | |
| 35 | Nurix Therapeutics Inc | 938 163 | 14,5 M $ | |
| 36 | Sionna Therapeutics Inc | 293 500 | 11,8 M $ | |
| 37 | Corcept Therapeutics Inc | 285 531 | 11,5 M $ | |
| 38 | JADE BIOSCIENCES INC | 796 744 | 11,2 M $ | |
| 39 | Veracyte Inc | 319 912 | 10,3 M $ | |
| 40 | Invivyd Inc | 7 708 727 | 10 M $ | |
| 41 | C4 Therapeutics Inc | 3 803 942 | 10 M $ | |
| 42 | OrthoPediatrics Corp | 615 447 | 9,8 M $ | |
| 43 | Arcus Biosciences Inc | 451 983 | 9,8 M $ | |
| 44 | Tango Therapeutics Inc | 450 000 | 9,4 M $ | |
| 45 | Evolus Inc | 2 245 360 | 9,2 M $ | |
| 46 | Enliven Therapeutics Inc | 230 869 | 9,1 M $ | |
| 47 | Inhibrx Biosciences Inc | 131 000 | 8,8 M $ | |
| 48 | Dexcom Inc | 140 000 | 8,8 M $ | |
| 49 | Septerna Inc | 275 000 | 6,6 M $ | |
| 50 | AVALO THERAPEUTICS INC | 441 978 | 6,6 M $ | |
| 51 | BIODESIX INC | 416 599 | 6 M $ | |
| 52 | Relmada Therapeutics Inc | 842 106 | 5,9 M $ | |
| 53 | Cullinan Therapeutics Inc | 410 200 | 5,8 M $ | |
| 54 | Immunovant Inc | 230 000 | 5,7 M $ | |
| 55 | MBX Biosciences Inc | 178 897 | 5,3 M $ | |
| 56 | IMMUNIC INC | 4 500 000 | 5 M $ | |
| 57 | Larimar Therapeutics Inc | 1 066 960 | 4,8 M $ | |
| 58 | Eton Pharmaceuticals Inc | 166 381 | 4,1 M $ | |
| 59 | SAB Biotherapeutics Inc | 1 050 000 | 4 M $ | |
| 60 | PROCEPT BIOROBOTICS CORP | 160 000 | 4 M $ | |
| 61 | Structure Therapeutics Inc | 80 000 | 3,9 M $ | |
| 62 | Tectonic Therapeutic Inc | 121 684 | 3,8 M $ | |
| 63 | Pulmonx Corp | 2 788 323 | 3,6 M $ | |
| 64 | Iovance Biotherapeutics Inc | 1 000 000 | 3,5 M $ | |
| 65 | Argenx SE | 3 500 | 2,6 M $ | |
| 66 | Karyopharm Therapeutics Inc | 440 000 | 2,5 M $ | |
| 67 | Arrowhead Pharmaceuticals Inc | 28 479 | 1,8 M $ | |
| 68 | InspireMD, Inc. | 1 045 708 | 1,7 M $ | |
| 69 | Insmed Inc | 10 250 | 1,7 M $ | |
| 70 | CytomX Therapeutics Inc | 300 000 | 1,4 M $ | |
| 71 | CG oncology Inc | 20 000 | 1,4 M $ | |
| 72 | NeoGenomics Inc | 175 000 | 1,3 M $ | |
| 73 | Cogent Biosciences Inc | 10 000 | 384,9 k $ | |
| 74 | Tyra Biosciences Inc | 10 000 | 383 k $ | |
| 75 | STAAR Surgical Co | 20 000 | 374 k $ | |
| 76 | AnaptysBio Inc | 6 000 | 332,8 k $ | |
| 77 | Rapport Therapeutics Inc | 10 000 | 312,9 k $ | |
| 78 | Rigel Pharmaceuticals Inc | 10 000 | 270,4 k $ | |
| 79 | Zymeworks Inc | 10 000 | 250,4 k $ | |
| 80 | LB Pharmaceuticals Inc | 10 000 | 246,6 k $ | |
| 81 | Oruka Therapeutics Inc | 5 000 | 245,3 k $ | |
| 82 | JASPER THERAPEUTICS INC | 276 312 | 242,1 k $ | |