| 1 | Abivax SA | 1 394 019 | 155,2 M $ | |
| 2 | Protagonist Therapeutics Inc | 994 119 | 104,8 M $ | |
| 3 | Immunovant Inc | 2 679 010 | 66,5 M $ | |
| 4 | State Street SPDR S&P 500 ETF Trust | 75 940 | 49,4 M $ | |
| 5 | Terns Pharmaceuticals Inc | 914 699 | 48,2 M $ | |
| 6 | Cytokinetics Inc | 632 556 | 41,7 M $ | |
| 7 | Crinetics Pharmaceuticals Inc | 1 139 331 | 41,4 M $ | |
| 8 | Alpha Architect 1-3 Month Box | 337 125 | 39,2 M $ | |
| 9 | Denali Therapeutics Inc | 1 871 455 | 35,9 M $ | |
| 10 | Beam Therapeutics Inc | 1 446 375 | 34,5 M $ | |
| 11 | ZAI LAB LTD | 1 425 367 | 26,8 M $ | |
| 12 | Septerna Inc | 1 089 818 | 26,2 M $ | |
| 13 | Vir Biotechnology Inc | 2 744 714 | 24,6 M $ | |
| 14 | DBV Technologies SA | 1 012 866 | 21,2 M $ | |
| 15 | Anteris Technologies Global Corp | 3 789 132 | 21 M $ | |
| 16 | Inspire Medical Systems Inc | 405 197 | 20,9 M $ | |
| 17 | Scholar Rock Holding Corp | 407 273 | 20 M $ | |
| 18 | Rhythm Pharmaceuticals Inc | 211 450 | 18,4 M $ | |
| 19 | Spyre Therapeutics Inc | 338 323 | 17,1 M $ | |
| 20 | CytomX Therapeutics Inc | 3 410 190 | 16 M $ | |
| 21 | Sanofi SA | 316 939 | 15,3 M $ | |
| 22 | Vaxcyte Inc | 259 137 | 15,1 M $ | |
| 23 | Monopar Therapeutics Inc | 264 278 | 14,5 M $ | |
| 24 | Amylyx Pharmaceuticals Inc | 1 000 604 | 13,9 M $ | |
| 25 | Celldex Therapeutics Inc | 427 816 | 13,6 M $ | |
| 26 | Taysha Gene Therapies Inc | 2 979 429 | 13,3 M $ | |
| 27 | Sutro Biopharma Inc | 524 441 | 13,1 M $ | |
| 28 | Revolution Medicines Inc | 133 893 | 13 M $ | |
| 29 | Enliven Therapeutics Inc | 329 540 | 12,9 M $ | |
| 30 | CG oncology Inc | 185 699 | 12,6 M $ | |
| 31 | SPDR Series Trust | 135 585 | 12,4 M $ | |
| 32 | Replimune Group Inc | 1 582 987 | 12,1 M $ | |
| 33 | Inventiva SACA | 2 174 398 | 12,1 M $ | |
| 34 | Ionis Pharmaceuticals Inc | 160 338 | 12 M $ | |
| 35 | Nektar Therapeutics | 161 252 | 11,6 M $ | |
| 36 | Inhibikase Therapeutics Inc | 6 606 572 | 11,1 M $ | |
| 37 | ARS Pharmaceuticals Inc | 1 361 536 | 10,9 M $ | |
| 38 | Ovid therapeutics Inc | 4 544 113 | 10,1 M $ | |
| 39 | OnKure Therapeutics Inc | 2 434 941 | 10,1 M $ | |
| 40 | Regeneron Pharmaceuticals, Inc. | 12 154 | 9,4 M $ | |
| 41 | Lexeo Therapeutics Inc | 1 467 350 | 8,4 M $ | |
| 42 | Opus Genetics Inc | 1 849 004 | 8,4 M $ | |
| 43 | Teva Pharmaceutical Industries Ltd | 268 391 | 8,1 M $ | |
| 44 | Savara Inc | 1 464 535 | 8 M $ | |
| 45 | MapLight Therapeutics Inc | 374 909 | 7,6 M $ | |
| 46 | LeonaBio Inc | 727 481 | 7,5 M $ | |
| 47 | Equillium Inc | 3 726 659 | 7,5 M $ | |
| 48 | Viking Therapeutics Inc | 227 717 | 7,4 M $ | |
| 49 | DAMORA THERAPEUTICS INC | 279 000 | 7,2 M $ | |
| 50 | Bridgebio Pharma Inc | 94 292 | 7 M $ | |
| 51 | Prime Medicine Inc | 1 973 282 | 6,9 M $ | |
| 52 | Vertex Pharmaceuticals Inc | 15 075 | 6,7 M $ | |
| 53 | Korro Bio Inc | 540 054 | 6,1 M $ | |
| 54 | Viridian Therapeutics Inc | 304 422 | 6 M $ | |
| 55 | Danaher Corp | 30 932 | 5,9 M $ | |
| 56 | Insmed Inc | 35 392 | 5,8 M $ | |
| 57 | Ascendis Pharma A/S | 25 014 | 5,7 M $ | |
| 58 | Brighthouse Financial Inc | 95 523 | 5,7 M $ | |
| 59 | Sarepta Therapeutics Inc | 262 058 | 5,7 M $ | |
| 60 | Krystal Biotech Inc | 20 014 | 5,2 M $ | |
| 61 | Acumen Pharmaceuticals Inc | 2 156 334 | 5,1 M $ | |
| 62 | Invivyd Inc | 3 822 427 | 5 M $ | |
| 63 | Protara Therapeutics Inc | 940 512 | 4,9 M $ | |
| 64 | Agios Pharmaceuticals Inc | 140 672 | 4,8 M $ | |
| 65 | Eli Lilly & Co | 5 060 | 4,7 M $ | |
| 66 | Dianthus Therapeutics Inc | 55 000 | 4,6 M $ | |
| 67 | Arrowhead Pharmaceuticals Inc | 70 300 | 4,4 M $ | |
| 68 | Belite Bio Inc | 26 880 | 4,3 M $ | |
| 69 | Evommune Inc | 184 062 | 4,2 M $ | |
| 70 | Mineralys Therapeutics Inc | 154 686 | 4,2 M $ | |
| 71 | Janux Therapeutics Inc | 298 546 | 4,1 M $ | |
| 72 | Climb Bio Inc | 597 662 | 4,1 M $ | |
| 73 | Palisade Bio Inc | 2 264 845 | 4 M $ | |
| 74 | SPRUCE BIOSCIENCES INC | 58 600 | 3,8 M $ | |
| 75 | Arcellx Inc | 32 084 | 3,7 M $ | |
| 76 | Contineum Therapeutics Inc | 276 661 | 3,6 M $ | |
| 77 | Monte Rosa Therapeutics Inc | 215 752 | 3,5 M $ | |
| 78 | BEONE MEDICINES LTD | 11 701 | 3,5 M $ | |
| 79 | Tenax Therapeutics Inc | 213 462 | 3,4 M $ | |
| 80 | ArriVent Biopharma Inc | 141 814 | 3,3 M $ | |
| 81 | Pliant Therapeutics Inc | 2 585 126 | 3,3 M $ | |
| 82 | AtaiBeckley Inc | 913 242 | 3,2 M $ | |
| 83 | Relmada Therapeutics Inc | 451 918 | 3,1 M $ | |
| 84 | Perspective Therapeutics Inc | 749 335 | 3,1 M $ | |
| 85 | Corbus Pharmaceuticals Holdings Inc | 331 781 | 3,1 M $ | |
| 86 | Eledon Pharmaceuticals Inc | 974 421 | 3 M $ | |
| 87 | Apellis Pharmaceuticals Inc | 72 500 | 2,9 M $ | |
| 88 | Edgewise Therapeutics Inc | 90 599 | 2,9 M $ | |
| 89 | PepGen Inc | 1 607 638 | 2,8 M $ | |
| 90 | Capricor Therapeutics Inc | 90 593 | 2,8 M $ | |
| 91 | Masimo Corp | 15 000 | 2,7 M $ | |
| 92 | INOVIO PHARMACEUTICALS INC | 1 470 108 | 2,6 M $ | |
| 93 | Teleflex Inc | 21 186 | 2,5 M $ | |
| 94 | BioAge Labs Inc | 135 560 | 2,4 M $ | |
| 95 | Alector Inc | 1 050 000 | 2,3 M $ | |
| 96 | Pfizer Inc | 77 400 | 2,2 M $ | |
| 97 | Delcath Systems Inc | 224 385 | 2,1 M $ | |
| 98 | Biogen Inc | 11 000 | 2 M $ | |
| 99 | Summit Therapeutics Inc | 91 869 | 1,7 M $ | |
| 100 | Globus Medical Inc | 20 100 | 1,7 M $ | |