| 1 | Revolution Medicines Inc | 2 375 000 | 231 M $ | |
| 2 | BioMarin Pharmaceutical Inc | 3 575 000 | 202 M $ | |
| 3 | Abivax SA | 1 500 000 | 167 M $ | |
| 4 | Neurocrine Biosciences Inc | 1 250 000 | 164,7 M $ | |
| 5 | Arrowhead Pharmaceuticals Inc | 2 275 000 | 142,6 M $ | |
| 6 | Enliven Therapeutics Inc | 3 250 000 | 127,4 M $ | |
| 7 | Repligen Corp | 925 000 | 109 M $ | |
| 8 | Bicara Therapeutics Inc | 5 425 000 | 107,9 M $ | |
| 9 | Nurix Therapeutics Inc | 6 500 000 | 100,8 M $ | |
| 10 | Apogee Therapeutics Inc | 1 100 000 | 92,6 M $ | |
| 11 | Ascendis Pharma A/S | 375 000 | 85,8 M $ | |
| 12 | Immunocore Holdings PLC | 2 766 868 | 83,4 M $ | |
| 13 | Taysha Gene Therapies Inc | 18 000 000 | 80,5 M $ | |
| 14 | Dyne Therapeutics Inc | 4 000 000 | 72,5 M $ | |
| 15 | Sanofi SA | 1 400 000 | 67,5 M $ | |
| 16 | BioCryst Pharmaceuticals Inc | 7 025 000 | 66,9 M $ | |
| 17 | Scholar Rock Holding Corp | 1 324 422 | 65,1 M $ | |
| 18 | Bristol-Myers Squibb Co | 1 000 000 | 60,7 M $ | |
| 19 | Monte Rosa Therapeutics Inc | 3 603 465 | 59,3 M $ | |
| 20 | Vera Therapeutics Inc | 1 368 159 | 55 M $ | |
| 21 | Terns Pharmaceuticals Inc | 1 000 000 | 52,7 M $ | |
| 22 | Globus Medical Inc | 610 520 | 52,6 M $ | |
| 23 | Boston Scientific Corp | 800 000 | 50,2 M $ | |
| 24 | Nuvalent Inc | 481 715 | 49,4 M $ | |
| 25 | Cogent Biosciences Inc | 1 230 888 | 47,4 M $ | |
| 26 | Alto Neuroscience Inc | 2 064 075 | 46,4 M $ | |
| 27 | Rapport Therapeutics Inc | 1 436 229 | 44,9 M $ | |
| 28 | Disc Medicine Inc | 700 000 | 44,8 M $ | |
| 29 | United Therapeutics Corp | 75 000 | 44,5 M $ | |
| 30 | Celldex Therapeutics Inc | 1 224 165 | 38,8 M $ | |
| 31 | KalVista Pharmaceuticals Inc | 1 850 000 | 37,2 M $ | |
| 32 | Solid Biosciences Inc | 5 000 000 | 36 M $ | |
| 33 | Protagonist Therapeutics Inc | 326 159 | 34,4 M $ | |
| 34 | Denali Therapeutics Inc | 1 773 326 | 34 M $ | |
| 35 | Regeneron Pharmaceuticals, Inc. | 40 000 | 30,9 M $ | |
| 36 | Waters Corp | 100 000 | 29,8 M $ | |
| 37 | Viking Therapeutics Inc | 914 147 | 29,7 M $ | |
| 38 | Inspire Medical Systems Inc | 539 269 | 27,8 M $ | |
| 39 | Trevi Therapeutics Inc | 2 166 504 | 25,8 M $ | |
| 40 | Lexeo Therapeutics Inc | 4 475 000 | 25,7 M $ | |
| 41 | Soleno Therapeutics Inc | 730 000 | 24,4 M $ | |
| 42 | Beta Bionics Inc | 2 211 518 | 22,2 M $ | |
| 43 | Nektar Therapeutics | 285 000 | 20,5 M $ | |
| 44 | Cytokinetics Inc | 300 000 | 19,8 M $ | |
| 45 | West Pharmaceutical Services Inc | 75 000 | 18,8 M $ | |
| 46 | GE HealthCare Technologies Inc | 250 000 | 17,8 M $ | |
| 47 | SpyGlass Pharma Inc | 666 760 | 17,3 M $ | |
| 48 | Zimmer Biomet Holdings Inc | 190 000 | 17,2 M $ | |
| 49 | Madrigal Pharmaceuticals Inc | 31 468 | 16,5 M $ | |
| 50 | GeneDx Holdings Corp | 250 000 | 16,1 M $ | |
| 51 | DAMORA THERAPEUTICS INC | 600 000 | 15,5 M $ | |
| 52 | Agios Pharmaceuticals Inc | 450 000 | 15,2 M $ | |
| 53 | Savara Inc | 2 600 052 | 14,2 M $ | |
| 54 | Tarsus Pharmaceuticals Inc | 200 000 | 14 M $ | |
| 55 | Voyager Therapeutics Inc | 3 002 936 | 11,6 M $ | |
| 56 | Insulet Corp | 50 601 | 10,6 M $ | |
| 57 | Tectonic Therapeutic Inc | 328 000 | 10,1 M $ | |
| 58 | Surrozen Inc | 338 611 | 9,9 M $ | |
| 59 | Arvinas Inc | 905 465 | 9,6 M $ | |
| 60 | MapLight Therapeutics Inc | 420 000 | 8,5 M $ | |
| 61 | Fulcrum Therapeutics Inc | 1 100 000 | 8,4 M $ | |
| 62 | OnKure Therapeutics Inc | 1 839 819 | 7,6 M $ | |
| 63 | Myriad Genetics Inc | 1 648 000 | 7,4 M $ | |
| 64 | Olema Pharmaceuticals Inc | 428 551 | 6,4 M $ | |
| 65 | Anteris Technologies Global Corp | 1 144 780 | 6,4 M $ | |
| 66 | Candel Therapeutics Inc | 1 125 000 | 5,5 M $ | |
| 67 | Palisade Bio Inc | 2 500 000 | 4,4 M $ | |
| 68 | Veracyte Inc | 130 687 | 4,2 M $ | |
| 69 | ZENAS BIOPHARMA INC | 200 000 | 3,9 M $ | |
| 70 | Geron Corp | 2 540 000 | 3,8 M $ | |
| 71 | Monopar Therapeutics Inc | 65 418 | 3,6 M $ | |
| 72 | Passage Bio Inc | 305 000 | 2,4 M $ | |
| 73 | Tyra Biosciences Inc | 54 000 | 2,1 M $ | |
| 74 | REGENXBIO Inc | 108 525 | 909,4 k $ | |
| 75 | Tenax Therapeutics Inc | 53 439 | 854,5 k $ | |
| 76 | MacroGenics Inc | 280 000 | 809,2 k $ | |
| 77 | Absci Corp | 232 219 | 696,7 k $ | |
| 78 | APREA THERAPEUTICS INC | 350 000 | 267 k $ | |