Funds holding Ionis Pharmaceuticals Inc
431 funds declare a position · 100 ETFs and 331 other funds · 6.6B $· 346.9M SEK· 4M € · US4622221004
Each line carries its report date.
| Rank | Fund | Shares | Value | Weight | |
|---|---|---|---|---|---|
| 301 | Fidelity Large Cap Value Index Fund Fidelity Salem Street Trust | 4,528 | 338.5K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 302 | Kennedy Capital ESG SMID Cap Fund INVESTMENT MANAGERS SERIES TRUST II | 4,504 | 338.2K $ | 0.47 % | as of Mar 31, 2026 · Original filing |
| 303 | SIIT LARGE CAP INDEX FUND SEI INSTITUTIONAL INVESTMENTS TRUST | 4,400 | 357.1K $ | 0.02 % | as of Feb 28, 2026 · Original filing |
| 304 | Alger Dynamic Opportunities Fund ALGER FUNDS II | 4,356 | 325.7K $ | 0.15 % | as of Apr 30, 2026 · Original filing |
| 305 | Calamos Timpani SMID Growth Fund CALAMOS INVESTMENT TRUST/IL | 4,355 | 325.6K $ | 0.69 % | as of Apr 30, 2026 · Original filing |
| 306 | MFS Blended Research Small Cap Equity Portfolio MFS VARIABLE INSURANCE TRUST III | 4,209 | 316.1K $ | 0.40 % | as of Mar 31, 2026 · Original filing |
| 307 | MOA ALL AMERICA FUND MoA Funds Corp | 4,071 | 305.7K $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 308 | Multimanager Aggressive Equity Portfolio EQ Advisors Trust | 4,000 | 300.4K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 309 | Goldman Sachs Future Health Care Equity ETF Goldman Sachs ETF Trust | 3,918 | 317.9K $ | 1.41 % | as of Feb 28, 2026 · Original filing |
| 310 | Fidelity Series Large Cap Value Index Fund Fidelity Salem Street Trust | 3,914 | 292.6K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 311 | VIP Total Market Index Portfolio Variable Insurance Products Fund II | 3,900 | 292.9K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 312 | Voya VACS Index Series MC Portfolio Voya VARIABLE PORTFOLIOS INC | 3,633 | 272.8K $ | 0.09 % | as of Mar 31, 2026 · Original filing |
| 313 | VOYA RUSSELLTM MID CAP GROWTH INDEX PORTFOLIO Voya VARIABLE PORTFOLIOS INC | 3,632 | 272.7K $ | 0.39 % | as of Mar 31, 2026 · Original filing |
| 314 | PD Mid-Cap Index Portfolio PACIFIC SELECT FUND | 3,613 | 271.3K $ | 0.09 % | as of Mar 31, 2026 · Original filing |
| 315 | MML Small Cap Growth Equity Fund MML SERIES INVESTMENT FUND | 3,524 | 264.6K $ | 0.20 % | as of Mar 31, 2026 · Original filing |
| 316 | MFS New Discovery Value Portfolio MFS VARIABLE INSURANCE TRUST III | 3,425 | 257.2K $ | 0.60 % | as of Mar 31, 2026 · Original filing |
| 317 | TIAA Separate Account VA-1 - Stock Index Account TIAA Separate Account VA-1 | 3,279 | 246.2K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 318 | Brighthouse/Wellington Balanced Portfolio Brighthouse Funds Trust II | 3,187 | 239.3K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 319 | Calvert U.S. Large Cap Growth Responsible Index Fund Calvert Responsible Index Series, Inc. | 3,054 | 229.3K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 320 | Fidelity Hedged Equity Fund Fidelity Greenwood Street Trust | 3,005 | 224.7K $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 321 | SIMT LARGE CAP INDEX FUND SEI INSTITUTIONAL MANAGED TRUST | 3,000 | 225.3K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 322 | AZL Russell 1000 Growth Index Fund Allianz Variable Insurance Products Trust | 2,793 | 209.7K $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 323 | NYLI U.S. Large Cap R&D Leaders ETF New York Life Investments ETF Trust | 2,788 | 208.4K $ | 0.07 % | as of Apr 30, 2026 · Original filing |
| 324 | BlackRock Global Allocation V.I. Fund BlackRock Variable Series Funds, Inc. | 2,636 | 197.9K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 325 | Total Stock Market Index Trust John Hancock Variable Insurance Trust | 2,514 | 188.8K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 326 | Motley Fool Next Index ETF RBB Fund, Inc. | 2,480 | 201.3K $ | 0.62 % | as of Feb 28, 2026 · Original filing |
| 327 | LISANTI SMALL CAP GROWTH FUND FORUM FUNDS | 2,465 | 185.1K $ | 1.33 % | as of Mar 31, 2026 · Original filing |
| 328 | Goldman Sachs MarketBeta(R) Russell 1000 Growth Equity ETF Goldman Sachs ETF Trust | 2,438 | 197.8K $ | 0.05 % | as of Feb 28, 2026 · Original filing |
| 329 | Calvert US Large-Cap Core Responsible Index ETF Morgan Stanley ETF Trust | 2,427 | 182.2K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 330 | Nuveen Life Stock Index Fund TIAA-CREF Life Funds | 2,335 | 175.3K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 331 | Fidelity OTC K6 Portfolio Fidelity Securities Fund | 2,327 | 174K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 332 | Growth Fund VALIC Co I | 2,320 | 188.3K $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 333 | Nuveen Large Cap Value Index Fund TIAA-CREF Funds | 2,299 | 171.9K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 334 | Harbor Health Care ETF Harbor ETF Trust | 2,153 | 161K $ | 0.58 % | as of Apr 30, 2026 · Original filing |
| 335 | THRIVENT MODERATELY AGGRESSIVE ALLOCATION PORTFOLIO Thrivent Series Fund, Inc. | 2,052 | 154.1K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 336 | Biotechnology Fund Rydex Variable Trust | 1,983 | 148.9K $ | 1.40 % | as of Mar 31, 2026 · Original filing |
| 337 | BlackRock Advantage Large Cap Value Fund BlackRock Large Cap Series Funds, Inc. | 1,936 | 157.1K $ | 0.02 % | as of Feb 27, 2026 · Original filing |
| 338 | Fidelity Mid Cap Value Index Fund Fidelity Salem Street Trust | 1,901 | 142.7K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 339 | First Trust Nasdaq Pharmaceuticals ETF First Trust Exchange-Traded Fund VI | 1,872 | 140.6K $ | 0.48 % | as of Mar 31, 2026 · Original filing |
| 340 | John Hancock Multifactor Large Cap ETF John Hancock Exchange-Traded Fund Trust | 1,825 | 137K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 341 | THRIVENT MODERATE ALLOCATION PORTFOLIO Thrivent Series Fund, Inc. | 1,703 | 127.9K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 342 | JNL/BlackRock Global Allocation Fund JNL Series Trust | 1,692 | 127.1K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 343 | SA T. Rowe Price Allocation Moderately Aggressive Portfolio SUNAMERICA SERIES TRUST | 1,624 | 121.4K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 344 | JNL/DFA U.S. Core Equity Fund JNL Series Trust | 1,615 | 121.3K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 345 | JNL/JPMorgan Global Allocation Fund JNL Series Trust | 1,602 | 120.3K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 346 | Catholic Values Equity Fund SEI CATHOLIC VALUES TRUST | 1,566 | 127.1K $ | 0.03 % | as of Feb 28, 2026 · Original filing |
| 347 | PIMCO RAFI Dynamic Multi-Factor U.S. Equity ETF PIMCO Equity Series | 1,501 | 112.7K $ | 0.05 % | as of Mar 31, 2026 · Original filing |
| 348 | Wilmington Large-Cap Strategy Fund Wilmington Funds | 1,480 | 110.6K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 349 | U.S. Social Core Equity 2 Portfolio DFA INVESTMENT DIMENSIONS GROUP INC | 1,476 | 110.3K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 350 | AVIP BlackRock Advantage Small Cap Growth Portfolio AuguStar Variable Insurance Products Fund Inc | 1,466 | 110.1K $ | 0.09 % | as of Mar 31, 2026 · Original filing |
| 351 | THRIVENT MODERATELY AGGRESSIVE ALLOCATION FUND Thrivent Mutual Funds | 1,413 | 105.6K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 352 | LVIP BlackRock Global Allocation Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST | 1,365 | 102.5K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 353 | Calvert US Mid-Cap Core Responsible Index ETF Morgan Stanley ETF Trust | 1,362 | 102.3K $ | 0.12 % | as of Mar 31, 2026 · Original filing |
| 354 | MFS Global Alternative Strategy Fund MFS Series Trust XV | 1,332 | 99.6K $ | 0.05 % | as of Apr 30, 2026 · Original filing |
| 355 | The Institutional U.S. Equity Portfolio HC Capital Trust | 1,266 | 95.1K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 356 | T. Rowe Price Spectrum Moderate Growth Allocation Fund T. ROWE PRICE SPECTRUM FUNDS II, INC. | 1,260 | 102.2K $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 357 | JPMorgan Healthcare Leaders ETF J.P. Morgan Exchange-Traded Fund Trust | 1,257 | 94K $ | 0.84 % | as of Apr 30, 2026 · Original filing |
| 358 | Health Care Fund Rydex Series Funds | 1,231 | 92.4K $ | 0.48 % | as of Mar 31, 2026 · Original filing |
| 359 | Dimensional US Sustainability Core 1 ETF Dimensional ETF Trust | 1,165 | 87.1K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 360 | Longboard Fund NORTHERN LIGHTS FUND TRUST II | 1,111 | 90.2K $ | 0.08 % | as of Feb 28, 2026 · Original filing |
| 361 | SIIT MULTI-ASSET REAL RETURN FUND SEI INSTITUTIONAL INVESTMENTS TRUST | 1,108 | 89.9K $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 362 | THRIVENT AGGRESSIVE ALLOCATION FUND Thrivent Mutual Funds | 1,056 | 78.9K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 363 | Victory Science & Technology Fund Victory Portfolios III | 1,036 | 77.5K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 364 | Gateway Equity Call Premium Fund Gateway Trust | 948 | 71.2K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 365 | State Street Balanced Index Fund STATE STREET INSTITUTIONAL INVESTMENT TRUST | 924 | 69.4K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 366 | State Street Total Return V.I.S. Fund STATE STREET VARIABLE INSURANCE SERIES FUNDS INC | 900 | 67.6K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 367 | THRIVENT AGGRESSIVE ALLOCATION PORTFOLIO Thrivent Series Fund, Inc. | 892 | 67K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 368 | Knights of Columbus U.S. ALL CAP INDEX FUND ADVISORS' INNER CIRCLE III | 879 | 65.7K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 369 | Destinations Small-Mid Cap Equity Fund Brinker Capital Destinations Trust | 859 | 69.7K $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 370 | T. Rowe Price Health Care ETF T. Rowe Price Exchange-Traded Funds, Inc. | 850 | 63.8K $ | 0.32 % | as of Mar 31, 2026 · Original filing |
| 371 | Multifactor U.S. Equity Fund RUSSELL INVESTMENT CO | 803 | 60K $ | 0.02 % | as of Apr 30, 2026 · Original filing |
| 372 | New Covenant Growth Fund NEW COVENANT FUNDS | 782 | 58.7K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 373 | AMT Diversified Equity Fund ADVISER MANAGED TRUST | 739 | 55.2K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 374 | EQ/Mid Cap Value Managed Volatility Portfolio EQ Advisors Trust | 702 | 52.7K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 375 | Wilshire 5000 Index Fund Wilshire Mutual Funds Inc | 700 | 52.6K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 376 | SIMT Multi-Asset Inflation Managed Fund SEI INSTITUTIONAL MANAGED TRUST | 694 | 52.1K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 377 | THRIVENT MODERATE ALLOCATION FUND Thrivent Mutual Funds | 684 | 51.1K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 378 | EQ/Large Cap Value Managed Volatility Portfolio EQ Advisors Trust | 670 | 50.3K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 379 | Health Care Fund Rydex Variable Trust | 645 | 48.4K $ | 0.39 % | as of Mar 31, 2026 · Original filing |
| 380 | WisdomTree BioRevolution Fund WisdomTree Trust | 621 | 46.6K $ | 2.06 % | as of Mar 31, 2026 · Original filing |
| 381 | THRIVENT GLOBAL STOCK FUND Thrivent Mutual Funds | 617 | 46.1K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 382 | THRIVENT MODERATELY CONSERVATIVE ALLOCATION PORTFOLIO Thrivent Series Fund, Inc. | 579 | 43.5K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 383 | LargeCap Growth Account I Principal Variable Contract Funds, Inc | 572 | 43K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 384 | LVIP Dimensional U.S. Core Equity 1 Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST | 553 | 41.5K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 385 | SA U.S. Core Market Fund SA FUNDS INVESTMENT TRUST | 541 | 40.6K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 386 | BNY Mellon Mid Cap Multi-Strategy Fund BNY MELLON FUNDS TRUST | 540 | 43.8K $ | 0.03 % | as of Feb 28, 2026 · Original filing |
| 387 | Strategic Allocation: Aggressive Fund American Century Strategic Asset Allocations Inc | 531 | 39.7K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 388 | T. Rowe Price Innovation Leaders ETF T. Rowe Price Exchange-Traded Funds, Inc. | 522 | 39.2K $ | 0.26 % | as of Mar 31, 2026 · Original filing |
| 389 | Virtus AlphaSimplex Global Alternatives Fund Virtus Alternative Solutions Trust | 521 | 39.1K $ | 0.05 % | as of Mar 31, 2026 · Original filing |
| 390 | THRIVENT GLOBAL STOCK PORTFOLIO Thrivent Series Fund, Inc. | 510 | 38.3K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 391 | Bridge Builder Large Cap Value Fund Bridge Builder Trust | 472 | 35.4K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 392 | Virtus Silvant Small/Mid Growth ETF Virtus ETF Trust II | 450 | 33.6K $ | 1.06 % | as of Apr 30, 2026 · Original filing |
| 393 | T. Rowe Price Spectrum Moderate Allocation Fund T. ROWE PRICE SPECTRUM FUNDS II, INC. | 435 | 35.3K $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 394 | Strategic Allocation: Moderate Fund American Century Strategic Asset Allocations Inc | 417 | 31.2K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 395 | Schwab U.S. Large-Cap Value Index Fund SCHWAB CAPITAL TRUST | 399 | 29.8K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 396 | American Century Small Cap Growth Insights ETF American Century ETF Trust | 397 | 32.2K $ | 0.36 % | as of Feb 28, 2026 · Original filing |
| 397 | GuideMark Small/Mid Cap Core Fund GPS Funds I | 385 | 28.9K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 398 | PD Large-Cap Value Index Portfolio PACIFIC SELECT FUND | 374 | 28.1K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 399 | EQ/Large Cap Value Index Portfolio EQ Advisors Trust | 357 | 26.8K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 400 | Fidelity Flex Mid Cap Focused Index Fund Fidelity Salem Street Trust | 325 | 24.3K $ | 0.17 % | as of Apr 30, 2026 · Original filing |
Institutional managers
483 managers declare this company to the SEC (Form 13F). These positions are not counted in the totals above: a manager and its own funds file separately.
| Manager | Shares | Value | |
|---|---|---|---|
| FMR LLC | 24,556,637 | 1.8B $ | as of Mar 31, 2026 |
| Capital World Investors | 21,186,369 | 1.6B $ | as of Mar 31, 2026 |
| BlackRock, Inc. | 10,442,476 | 784.1M $ | as of Mar 31, 2026 |
| WELLINGTON MANAGEMENT GROUP LLP | 6,391,816 | 480M $ | as of Mar 31, 2026 |
| TWO SIGMA INVESTMENTS, LP | 5,857,629 | 439.8M $ | as of Mar 31, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | 3,984,332 | 305.2M $ | as of Mar 31, 2026 |
| STATE STREET CORP | 3,995,564 | 300M $ | as of Mar 31, 2026 |
| ROYAL BANK OF CANADA | 3,801,815 | 285.5M $ | as of Mar 31, 2026 |
| JPMORGAN CHASE & CO | 2,363,567 | 171.4M $ | as of Mar 31, 2026 |
| Tweedy, Browne Co LLC | 2,275,625 | 170.9M $ | as of Mar 31, 2026 |
| Artisan Partners Limited Partnership | 2,058,308 | 154.6M $ | as of Mar 31, 2026 |
| BAKER BROS. ADVISORS LP | 2,047,727 | 153.8M $ | as of Mar 31, 2026 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1,979,669 | 148.7M $ | as of Mar 31, 2026 |
| Deep Track Capital, LP | 1,950,000 | 146.4M $ | as of Mar 31, 2026 |
| Bellevue Group AG | 1,818,665 | 136.6M $ | as of Mar 31, 2026 |
| GOLDMAN SACHS GROUP INC | 1,699,847 | 127.6M $ | as of Mar 31, 2026 |
| AMERICAN CENTURY COMPANIES INC | 1,663,803 | 124.9M $ | as of Mar 31, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,583,266 | 118.9M $ | as of Mar 31, 2026 |
| FRANKLIN RESOURCES INC | 1,575,023 | 118.3M $ | as of Mar 31, 2026 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,475,632 | 110.8M $ | as of Mar 31, 2026 |
| Pictet Asset Management Holding SA | 1,434,995 | 107.1M $ | as of Mar 31, 2026 |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 1,404,033 | 105.4M $ | as of Mar 31, 2026 |
| Invesco Ltd. | 1,277,358 | 95.9M $ | as of Mar 31, 2026 |
| MILLENNIUM MANAGEMENT LLC | 1,051,506 | 79M $ | as of Mar 31, 2026 |
| MORGAN STANLEY | 1,026,509 | 77.1M $ | as of Mar 31, 2026 |