Funds holding Tyra Biosciences Inc
169 funds declare a position · 33 ETFs and 136 other funds · 472.9M $ · US90240B1061
Each line carries its report date.
| Rank | Fund | Shares | Value | Weight | |
|---|---|---|---|---|---|
| 1 | Fidelity OTC Portfolio Fidelity Securities Fund | 3,279,300 | 114M $ | 0.28 % | as of Apr 30, 2026 · Original filing |
| 2 | VANGUARD TOTAL STOCK MARKET INDEX FUND VANGUARD INDEX FUNDS | 836,172 | 32M $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 3 | State Street(R) SPDR(R) S&P(R) Biotech ETF SPDR SERIES TRUST | 655,457 | 25.1M $ | 0.34 % | as of Mar 31, 2026 · Original filing |
| 4 | iShares Russell 2000 ETF iShares Trust | 636,602 | 24.4M $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 5 | VIP Growth Portfolio Variable Insurance Products Fund | 518,000 | 19.8M $ | 0.19 % | as of Mar 31, 2026 · Original filing |
| 6 | Fidelity Stock Selector Small Cap Fund Fidelity Capital Trust | 389,600 | 13.5M $ | 0.20 % | as of Apr 30, 2026 · Original filing |
| 7 | Fidelity Small Cap Growth Fund Fidelity Securities Fund | 374,540 | 13M $ | 0.15 % | as of Apr 30, 2026 · Original filing |
| 8 | Fidelity Advisor Biotechnology Fund Fidelity Advisor Series VII | 354,200 | 12.3M $ | 0.65 % | as of Apr 30, 2026 · Original filing |
| 9 | Janus Henderson Triton Fund JANUS INVESTMENT FUND | 351,278 | 13.5M $ | 0.26 % | as of Mar 31, 2026 · Original filing |
| 10 | T. Rowe Price Health Sciences Fund, Inc. T. ROWE PRICE HEALTH SCIENCES FUND, INC. | 307,082 | 11.8M $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 11 | Fidelity OTC K6 Portfolio Fidelity Securities Fund | 288,300 | 10M $ | 0.30 % | as of Apr 30, 2026 · Original filing |
| 12 | Fidelity Growth Discovery Fund Fidelity Hastings Street Trust | 280,800 | 10.8M $ | 0.19 % | as of Mar 31, 2026 · Original filing |
| 13 | Fidelity Series Small Cap Opportunities Fund Fidelity Securities Fund | 274,200 | 9.5M $ | 0.19 % | as of Apr 30, 2026 · Original filing |
| 14 | iShares Biotechnology ETF iShares Trust | 272,474 | 10.4M $ | 0.13 % | as of Mar 31, 2026 · Original filing |
| 15 | VANGUARD EXTENDED MARKET INDEX FUND VANGUARD INDEX FUNDS | 262,408 | 10.1M $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 16 | Fidelity Small Cap Index Fund Fidelity Salem Street Trust | 256,044 | 8.9M $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 17 | Fidelity Fund Fidelity Hastings Street Trust | 248,500 | 9.5M $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 18 | iShares Russell 2000 Value ETF iShares Trust | 222,011 | 8.5M $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 19 | T. Rowe Price New Horizons Fund, Inc. T. ROWE PRICE NEW HORIZONS FUND, INC. | 221,482 | 8.5M $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 20 | Janus Henderson Venture Fund JANUS INVESTMENT FUND | 204,289 | 7.8M $ | 0.26 % | as of Mar 31, 2026 · Original filing |
| 21 | Fidelity Small Cap Growth K6 Fund Fidelity Securities Fund | 191,359 | 6.6M $ | 0.16 % | as of Apr 30, 2026 · Original filing |
| 22 | PGIM Jennison Health Sciences Fund Prudential Sector Funds, Inc. | 182,879 | 6.1M $ | 0.42 % | as of Feb 27, 2026 · Original filing |
| 23 | T. Rowe Price Integrated U.S. Small-Cap Growth Equity Fund T. ROWE PRICE INTEGRATED EQUITY FUNDS, INC. | 160,400 | 6.1M $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 24 | Fidelity Advisor Health Care Fund Fidelity Advisor Series VII | 140,000 | 4.9M $ | 0.17 % | as of Apr 30, 2026 · Original filing |
| 25 | VANGUARD RUSSELL 2000 INDEX FUND VANGUARD SCOTTSDALE FUNDS | 128,334 | 4.3M $ | 0.03 % | as of Feb 28, 2026 · Original filing |
| 26 | Fidelity Extended Market Index Fund Fidelity Concord Street Trust | 123,768 | 4.1M $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 27 | Schwab U.S. Small-Cap ETF SCHWAB STRATEGIC TRUST | 113,175 | 3.8M $ | 0.02 % | as of Feb 28, 2026 · Original filing |
| 28 | NORTH SQUARE DYNAMIC SMALL CAP FUND Exchange Place Advisors Trust | 72,914 | 2.4M $ | 0.35 % | as of Feb 28, 2026 · Original filing |
| 29 | iShares Micro-Cap ETF iShares Trust | 65,304 | 2.5M $ | 0.21 % | as of Mar 31, 2026 · Original filing |
| 30 | VANGUARD U.S. MOMENTUM FACTOR ETF VANGUARD WELLINGTON FUND | 57,782 | 1.9M $ | 0.14 % | as of Feb 28, 2026 · Original filing |
| 31 | Schwab Small-Cap Index Fund SCHWAB CAPITAL TRUST | 56,685 | 2M $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 32 | Nuveen Quant Small Cap Equity Fund TIAA-CREF Funds | 55,409 | 1.9M $ | 0.05 % | as of Apr 30, 2026 · Original filing |
| 33 | Invesco Dorsey Wright SmallCap Momentum ETF Invesco Exchange-Traded Fund Trust II | 54,307 | 1.8M $ | 0.47 % | as of Feb 28, 2026 · Original filing |
| 34 | Invesco Dorsey Wright Healthcare Momentum ETF Invesco Exchange-Traded Fund Trust | 53,591 | 1.9M $ | 1.54 % | as of Apr 30, 2026 · Original filing |
| 35 | VIP Health Care Portfolio Variable Insurance Products Fund IV | 50,000 | 1.9M $ | 0.19 % | as of Mar 31, 2026 · Original filing |
| 36 | ALPS Medical Breakthroughs ETF ALPS ETF TRUST | 47,570 | 1.6M $ | 1.15 % | as of Feb 28, 2026 · Original filing |
| 37 | Avantis U.S. Small Cap Equity ETF American Century ETF Trust | 47,506 | 1.6M $ | 0.07 % | as of Feb 28, 2026 · Original filing |
| 38 | Fidelity Total Market Index Fund Fidelity Concord Street Trust | 45,795 | 1.5M $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 39 | Multi-Manager Small Cap Equity Strategies Fund COLUMBIA FUNDS SERIES TRUST I | 44,460 | 1.5M $ | 0.12 % | as of Feb 28, 2026 · Original filing |
| 40 | Master Small Cap Index Series Quantitative Master Series LLC | 41,730 | 1.6M $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 41 | VANGUARD HEALTH CARE INDEX FUND VANGUARD WORLD FUND | 40,280 | 1.3M $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 42 | SMALL CAP EQUITY FUND GuideStone Funds | 38,137 | 1.5M $ | 0.18 % | as of Mar 31, 2026 · Original filing |
| 43 | Direxion Daily S&P Biotech Bull 3X Shares Direxion Shares ETF Trust | 37,514 | 1.3M $ | 0.25 % | as of Apr 30, 2026 · Original filing |
| 44 | Fidelity Nasdaq Composite Index Fund Fidelity Concord Street Trust | 36,311 | 1.2M $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 45 | Fidelity Series Total Market Index Fund Fidelity Concord Street Trust | 34,732 | 1.2M $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 46 | Fidelity Fundamental Small-Mid Cap ETF Fidelity Covington Trust | 33,120 | 1.2M $ | 0.09 % | as of Apr 30, 2026 · Original filing |
| 47 | Fidelity Small Cap Value Index Fund Fidelity Salem Street Trust | 32,050 | 1.2M $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 48 | U.S. SMALL CAP PORTFOLIO DFA INVESTMENT DIMENSIONS GROUP INC | 31,755 | 1.1M $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 49 | Nuveen Small Cap Blend Index Fund TIAA-CREF Funds | 31,231 | 1.1M $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 50 | iShares Core S&P Total U.S. Stock Market ETF iShares Trust | 30,622 | 1.2M $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 51 | Tema Oncology ETF Tema ETF Trust | 28,438 | 947.3K $ | 0.59 % | as of Feb 28, 2026 · Original filing |
| 52 | EQ/2000 Managed Volatility Portfolio EQ Advisors Trust | 27,685 | 1.1M $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 53 | T. Rowe Price Integrated U.S. Small-Mid Cap Core Equity Fund T. ROWE PRICE INTEGRATED EQUITY FUNDS, INC. | 25,442 | 974.4K $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 54 | Goldman Sachs Small Cap Value Insights Fund Goldman Sachs Trust | 24,034 | 835.2K $ | 0.07 % | as of Apr 30, 2026 · Original filing |
| 55 | Fidelity Nasdaq Composite Index ETF Fidelity Commonwealth Trust | 23,065 | 768.3K $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 56 | NVIT Small Cap Value Fund Nationwide Variable Insurance Trust | 22,743 | 871.1K $ | 0.46 % | as of Mar 31, 2026 · Original filing |
| 57 | JPMorgan U.S. Small Company Fund JPMorgan Trust I | 19,944 | 763.9K $ | 0.08 % | as of Mar 31, 2026 · Original filing |
| 58 | T.Rowe Price Small Cap Growth Portfolio Brighthouse Funds Trust II | 19,200 | 735.4K $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 59 | VANGUARD RUSSELL 2000 VALUE INDEX FUND VANGUARD SCOTTSDALE FUNDS | 19,192 | 639.3K $ | 0.06 % | as of Feb 28, 2026 · Original filing |
| 60 | T. Rowe Price Health Sciences Portfolio T. ROWE PRICE EQUITY SERIES, INC. | 18,800 | 720K $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 61 | EQ/Small Company Index Portfolio EQ Advisors Trust | 17,650 | 676K $ | 0.04 % | as of Mar 31, 2026 · Original filing |
| 62 | Schwab Total Stock Market Index Fund SCHWAB CAPITAL TRUST | 15,817 | 549.6K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 63 | LVIP SSGA Small-Cap Index Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST | 15,400 | 589.8K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 64 | Tax-Managed U.S. Mid & Small Cap Fund RUSSELL INVESTMENT CO | 15,376 | 534.3K $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 65 | Nuveen Equity Index Fund TIAA-CREF Funds | 15,373 | 534.2K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 66 | VANGUARD BALANCED INDEX FUND VANGUARD VALLEY FORGE FUNDS | 14,697 | 562.9K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 67 | U.S. Small Cap Equity Fund RUSSELL INVESTMENT CO | 14,318 | 497.6K $ | 0.05 % | as of Apr 30, 2026 · Original filing |
| 68 | NVIT Multi-Manager Small Company Fund Nationwide Variable Insurance Trust | 13,785 | 528K $ | 0.15 % | as of Mar 31, 2026 · Original filing |
| 69 | U.S. MICRO CAP PORTFOLIO DFA INVESTMENT DIMENSIONS GROUP INC | 13,664 | 474.8K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 70 | Schwab U.S. Broad Market ETF SCHWAB STRATEGIC TRUST | 13,115 | 436.9K $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 71 | LVIP Franklin Templeton Multi-Factor SMID Cap Equity Fund LINCOLN VARIABLE INSURANCE PRODUCTS TRUST | 12,970 | 496.8K $ | 0.05 % | as of Mar 31, 2026 · Original filing |
| 72 | Dimensional U.S. Small Cap ETF Dimensional ETF Trust | 12,741 | 442.7K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 73 | Fidelity ZERO Total Market Index Fund Fidelity Concord Street Trust | 12,677 | 440.5K $ | 0.00 % | as of Apr 30, 2026 · Original filing |
| 74 | VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND VANGUARD INSTITUTIONAL INDEX FUNDS | 12,541 | 480.3K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 75 | Transamerica T. Rowe Price Small Cap VP TRANSAMERICA SERIES TRUST | 12,500 | 478.8K $ | 0.08 % | as of Mar 31, 2026 · Original filing |
| 76 | Virtus Biotech Clinical Trials Etf ETFis Series Trust I | 12,196 | 423.8K $ | 1.14 % | as of Apr 30, 2026 · Original filing |
| 77 | Small Cap Index Fund Northern Funds | 12,173 | 466.2K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 78 | EQ/AB Small Cap Growth Portfolio EQ Advisors Trust | 12,060 | 461.9K $ | 0.02 % | as of Mar 31, 2026 · Original filing |
| 79 | BIOTECHNOLOGY ULTRASECTOR PROFUND ProFunds | 11,611 | 403.5K $ | 0.22 % | as of Apr 30, 2026 · Original filing |
| 80 | Bridge Builder Small/Mid Cap Value Fund Bridge Builder Trust | 11,387 | 436.1K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 81 | Global X Russell 2000 ETF GLOBAL X FUNDS | 11,184 | 388.6K $ | 0.03 % | as of Apr 30, 2026 · Original filing |
| 82 | VIP Disciplined Small Cap Portfolio Variable Insurance Products Fund II | 10,724 | 410.7K $ | 0.08 % | as of Mar 31, 2026 · Original filing |
| 83 | Small Cap Index Fund VALIC Co I | 10,279 | 342.4K $ | 0.03 % | as of Feb 28, 2026 · Original filing |
| 84 | STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO STATE STREET INSTITUTIONAL INVESTMENT TRUST | 9,107 | 348.8K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 85 | Fidelity ZERO Extended Market Index Fund Fidelity Concord Street Trust | 8,229 | 286K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 86 | MetLife Russell 2000 Index Portfolio Brighthouse Funds Trust II | 8,096 | 310.1K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 87 | ATM Small Cap Managed Volatility Portfolio EQ Advisors Trust | 7,812 | 299.2K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 88 | Health Sciences Trust John Hancock Variable Insurance Trust | 6,900 | 264.3K $ | 0.12 % | as of Mar 31, 2026 · Original filing |
| 89 | Small-Cap Index Portfolio PACIFIC SELECT FUND | 6,615 | 253.4K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 90 | iShares Russell 3000 ETF iShares Trust | 6,571 | 251.7K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 91 | Fidelity MSCI Health Care Index ETF FIDELITY COVINGTON TRUST | 6,122 | 212.7K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 92 | ACUITAS US MICROCAP FUND FORUM FUNDS II | 6,078 | 232.8K $ | 0.24 % | as of Mar 31, 2026 · Original filing |
| 93 | Penn Series Small Cap Growth Fund Penn Series Funds Inc | 5,930 | 227.1K $ | 0.26 % | as of Mar 31, 2026 · Original filing |
| 94 | NVIT Small Cap Index Fund Nationwide Variable Insurance Trust | 5,071 | 194.2K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 95 | Fidelity Small Cap Discovery Fund Fidelity Concord Street Trust | 4,900 | 170.3K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 96 | EQ/T.Rowe Price Health Sciences Portfolio EQ Advisors Trust | 4,800 | 183.8K $ | 0.12 % | as of Mar 31, 2026 · Original filing |
| 97 | Small Cap Index Trust John Hancock Variable Insurance Trust | 4,721 | 180.8K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 98 | 1290 VT Micro Cap Portfolio EQ Advisors Trust | 4,662 | 178.6K $ | 0.10 % | as of Mar 31, 2026 · Original filing |
| 99 | iShares Russell Small/Mid-Cap Index Fund BlackRock Funds | 4,400 | 152.9K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 100 | Small Cap Core Fund Northern Funds | 4,389 | 168.1K $ | 0.05 % | as of Mar 31, 2026 · Original filing |
Institutional managers
156 managers declare this company to the SEC (Form 13F). These positions are not counted in the totals above: a manager and its own funds file separately.
| Manager | Shares | Value | |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 12,198,625 | 467.2M $ | as of Mar 31, 2026 |
| FMR LLC | 7,747,648 | 296.7M $ | as of Mar 31, 2026 |
| Nextech Invest, Ltd. | 4,055,861 | 155.3M $ | as of Mar 31, 2026 |
| JANUS HENDERSON GROUP PLC | 3,890,589 | 148.9M $ | as of Mar 31, 2026 |
| Alta Partners Management Company, L.P. | 3,823,425 | 146.4M $ | as of Mar 31, 2026 |
| FARALLON CAPITAL MANAGEMENT LLC | 3,580,818 | 137.1M $ | as of Mar 31, 2026 |
| TCG Crossover Management, LLC | 3,248,980 | 124.4M $ | as of Mar 31, 2026 |
| Commodore Capital LP | 2,475,000 | 94.8M $ | as of Mar 31, 2026 |
| BlackRock, Inc. | 2,217,929 | 84.9M $ | as of Mar 31, 2026 |
| Paradigm Biocapital Advisors LP | 2,054,991 | 78.7M $ | as of Mar 31, 2026 |
| BVF INC/IL | 1,976,196 | 75.7M $ | as of Mar 31, 2026 |
| Caligan Partners LP | 1,276,968 | 48.9M $ | as of Mar 31, 2026 |
| STATE STREET CORP | 1,216,078 | 46.6M $ | as of Mar 31, 2026 |
| 5AM Venture Management, LLC | 1,029,298 | 39.4M $ | as of Mar 31, 2026 |
| Logos Global Management LP | 850,000 | 32.6M $ | as of Mar 31, 2026 |
| BARCLAYS PLC | 833,399 | 31.9M $ | as of Mar 31, 2026 |
| Canaan Partners XI LLC | 750,000 | 28.7M $ | as of Mar 31, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | 658,482 | 25.2M $ | as of Mar 31, 2026 |
| JENNISON ASSOCIATES LLC | 632,432 | 24.2M $ | as of Mar 31, 2026 |
| Sio Capital Management, LLC | 605,439 | 23.2M $ | as of Mar 31, 2026 |
| GOLDMAN SACHS GROUP INC | 550,334 | 21.1M $ | as of Mar 31, 2026 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 549,000 | 21M $ | as of Mar 31, 2026 |
| Balyasny Asset Management L.P. | 351,479 | 13.5M $ | as of Mar 31, 2026 |
| Elmind Capital, LP | 350,000 | 13.4M $ | as of Mar 31, 2026 |
| Woodline Partners LP | 301,040 | 11.5M $ | as of Mar 31, 2026 |