| 1 | Praxis Precision Medicines Inc | 2 035 986 | 656 M $ | |
| 2 | Celcuity Inc | 3 127 200 | 356,9 M $ | |
| 3 | Ascendis Pharma A/S | 1 531 421 | 350,3 M $ | |
| 4 | CENTESSA PHARMACEUTICALS PLC | 5 258 903 | 208,9 M $ | |
| 5 | Rhythm Pharmaceuticals Inc | 2 373 795 | 206,4 M $ | |
| 6 | Spyre Therapeutics Inc | 3 783 225 | 190,8 M $ | |
| 7 | Nuvalent Inc | 1 580 505 | 161,9 M $ | |
| 8 | Edgewise Therapeutics Inc | 4 423 974 | 139,4 M $ | |
| 9 | Protagonist Therapeutics Inc | 1 230 879 | 129,7 M $ | |
| 10 | Apogee Therapeutics Inc | 1 540 384 | 129,7 M $ | |
| 11 | Travere Therapeutics Inc | 4 142 551 | 123,1 M $ | |
| 12 | Amylyx Pharmaceuticals Inc | 8 284 882 | 115,2 M $ | |
| 13 | Relay Therapeutics Inc | 9 751 141 | 97 M $ | |
| 14 | Inhibrx Biosciences Inc | 1 442 707 | 97 M $ | |
| 15 | Zymeworks Inc | 3 510 078 | 87,9 M $ | |
| 16 | Solid Biosciences Inc | 11 906 646 | 85,7 M $ | |
| 17 | Dyne Therapeutics Inc | 4 668 839 | 84,6 M $ | |
| 18 | BioCryst Pharmaceuticals Inc | 7 434 033 | 70,8 M $ | |
| 19 | Oruka Therapeutics Inc | 1 395 501 | 68,4 M $ | |
| 20 | Artivion Inc | 1 637 290 | 60 M $ | |
| 21 | Nurix Therapeutics Inc | 3 710 877 | 57,5 M $ | |
| 22 | Nautilus Biotechnology Inc | 12 594 211 | 48,9 M $ | |
| 23 | CytomX Therapeutics Inc | 10 098 824 | 47,5 M $ | |
| 24 | Alto Neuroscience Inc | 2 009 893 | 45,2 M $ | |
| 25 | Immunovant Inc | 1 597 383 | 39,7 M $ | |
| 26 | Intuitive Surgical Inc | 85 419 | 39,4 M $ | |
| 27 | Ionis Pharmaceuticals Inc | 504 000 | 37,8 M $ | |
| 28 | Day One Biopharmaceuticals Inc | 1 755 799 | 37,6 M $ | |
| 29 | Abivax SA | 328 884 | 36,6 M $ | |
| 30 | Corvus Pharmaceuticals Inc | 2 292 441 | 33,5 M $ | |
| 31 | Repligen Corp | 280 541 | 33,1 M $ | |
| 32 | DAMORA THERAPEUTICS INC | 1 223 000 | 31,7 M $ | |
| 33 | X4 PHARMACEUTICALS INC | 6 737 648 | 27,8 M $ | |
| 34 | Guardant Health Inc | 300 000 | 27,7 M $ | |
| 35 | Invivyd Inc | 20 859 303 | 27,1 M $ | |
| 36 | Sionna Therapeutics Inc | 658 439 | 26,4 M $ | |
| 37 | Axsome Therapeutics Inc | 149 950 | 25,3 M $ | |
| 38 | Revolution Medicines Inc | 258 600 | 25,1 M $ | |
| 39 | SAB Biotherapeutics Inc | 6 431 743 | 24,6 M $ | |
| 40 | Belite Bio Inc | 151 979 | 24,2 M $ | |
| 41 | Tenax Therapeutics Inc | 1 447 782 | 23,2 M $ | |
| 42 | Axogen Inc | 697 312 | 23,1 M $ | |
| 43 | Viridian Therapeutics Inc | 1 170 829 | 22,9 M $ | |
| 44 | Orchestra BioMed Holdings Inc | 5 037 906 | 21,4 M $ | |
| 45 | Rapport Therapeutics Inc | 673 923 | 21,1 M $ | |
| 46 | DBV Technologies SA | 964 391 | 20,1 M $ | |
| 47 | LeonaBio Inc | 1 859 322 | 19,1 M $ | |
| 48 | Anteris Technologies Global Corp | 3 425 476 | 19 M $ | |
| 49 | Sutro Biopharma Inc | 715 307 | 17,8 M $ | |
| 50 | Tango Therapeutics Inc | 808 153 | 16,9 M $ | |
| 51 | Contineum Therapeutics Inc | 1 255 592 | 16,4 M $ | |
| 52 | Palisade Bio Inc | 8 928 149 | 15,6 M $ | |
| 53 | IRhythm Holdings Inc | 105 026 | 12,4 M $ | |
| 54 | ADAGIO MEDICAL HOLDINGS INC | 9 876 576 | 11 M $ | |
| 55 | Evommune Inc | 448 350 | 10,3 M $ | |
| 56 | Phathom Pharmaceuticals Inc | 925 000 | 10,3 M $ | |
| 57 | Neumora Therapeutics Inc | 5 104 097 | 10 M $ | |
| 58 | Omada Health Inc | 786 330 | 9,9 M $ | |
| 59 | Neurocrine Biosciences Inc | 65 050 | 8,6 M $ | |
| 60 | Beta Bionics Inc | 842 944 | 8,4 M $ | |
| 61 | Opus Genetics Inc | 1 835 842 | 8,4 M $ | |
| 62 | Billiontoone Inc | 91 812 | 7,2 M $ | |
| 63 | Twist Bioscience Corp | 150 000 | 7,1 M $ | |
| 64 | Surrozen Inc | 229 393 | 6,7 M $ | |
| 65 | AGOMAB THERAPEUTICS SA | 600 000 | 6,3 M $ | |
| 66 | Evolus Inc | 1 286 862 | 5,3 M $ | |
| 67 | Cogent Biosciences Inc | 121 082 | 4,7 M $ | |
| 68 | ADMA Biologics Inc | 467 233 | 4,2 M $ | |
| 69 | Inhibikase Therapeutics Inc | 2 315 000 | 3,9 M $ | |
| 70 | Apellis Pharmaceuticals Inc | 80 956 | 3,3 M $ | |
| 71 | Outset Medical Inc | 833 333 | 3,2 M $ | |
| 72 | Adaptive Biotechnologies Corp | 152 500 | 2,1 M $ | |
| 73 | AVALO THERAPEUTICS INC | 139 667 | 2,1 M $ | |
| 74 | Corcept Therapeutics Inc | 50 000 | 2 M $ | |
| 75 | Medline Inc | 28 000 | 1,2 M $ | |
| 76 | PALATIN TECHNOLOGIES INC | 61 945 | 1,1 M $ | |
| 77 | Cumberland Pharmaceuticals Inc | 196 978 | 640,2 k $ | |
| 78 | REVOLUTION MEDICINES INC WTS 12/26 | 250 000 | 447,5 k $ | |
| 79 | Exagen Inc | 114 893 | 344,7 k $ | |
| 80 | ENSYSCE BIOSCIENCES INC | 86 666 | 46,7 k $ | |