Funds holding Spyre Therapeutics Inc
227 funds declare a position · 41 ETFs and 186 other funds · 1.4B $· 33M SEK · US00773J2024
Other lines from the same issuer : Spyre Therapeutics, Inc. (US007CVR0207)
Each line carries its report date.
| Rank | Fund | Shares | Value | Weight | |
|---|---|---|---|---|---|
| 201 | Nuveen Life Stock Index Fund TIAA-CREF Life Funds | 538 | 27.1K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 202 | Goldman Sachs Small Cap Growth Insights Fund Goldman Sachs Trust | 517 | 38.5K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 203 | T. Rowe Price Innovation Leaders ETF T. Rowe Price Exchange-Traded Funds, Inc. | 480 | 24.2K $ | 0.16 % | as of Mar 31, 2026 · Original filing |
| 204 | Small Company Value Portfolio Wilshire Mutual Funds Inc | 450 | 22.7K $ | 0.10 % | as of Mar 31, 2026 · Original filing |
| 205 | Knights of Columbus U.S. ALL CAP INDEX FUND ADVISORS' INNER CIRCLE III | 369 | 27.5K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 206 | Wilshire 5000 Index Fund Wilshire Mutual Funds Inc | 352 | 17.8K $ | 0.01 % | as of Mar 31, 2026 · Original filing |
| 207 | Russell 2000 2x Strategy Fund Rydex Dynamic Funds | 342 | 17.3K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 208 | State Street(R) SPDR(R) Portfolio MSCI Global Stock Market ETF SPDR INDEX SHARES FUNDS | 305 | 15.4K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 209 | State Street Balanced Index Fund STATE STREET INSTITUTIONAL INVESTMENT TRUST | 305 | 15.4K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 210 | Innovator U.S. Small Cap Managed 10 Buffer ETF Innovator ETFs Trust | 240 | 17.9K $ | 0.23 % | as of Apr 30, 2026 · Original filing |
| 211 | PROFUND VP ULTRA SMALL CAP ProFunds | 230 | 11.6K $ | 0.08 % | as of Mar 31, 2026 · Original filing |
| 212 | Goldman Sachs Absolute Return Tracker Fund GOLDMAN SACHS TRUST | 224 | 11.3K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 213 | Gotham Absolute Return Fund FundVantage Trust | 191 | 9.6K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 214 | PROFUND VP SMALL CAP ProFunds | 174 | 8.8K $ | 0.07 % | as of Mar 31, 2026 · Original filing |
| 215 | Russell 2000 Fund Rydex Series Funds | 157 | 7.9K $ | 0.06 % | as of Mar 31, 2026 · Original filing |
| 216 | SMALL-CAP PROFUND ProFunds | 136 | 10.1K $ | 0.13 % | as of Apr 30, 2026 · Original filing |
| 217 | E*TRADE No Fee Total Market Index Fund E Trade Trust | 134 | 10K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 218 | Small Company Growth Portfolio Wilshire Mutual Funds Inc | 125 | 6.3K $ | 0.03 % | as of Mar 31, 2026 · Original filing |
| 219 | Russell 2000 1.5x Strategy Fund Rydex Series Funds | 94 | 4.7K $ | 0.08 % | as of Mar 31, 2026 · Original filing |
| 220 | Fidelity Series Sustainable U.S. Market Fund Fidelity Summer Street Trust | 93 | 6.9K $ | 0.01 % | as of Apr 30, 2026 · Original filing |
| 221 | ProShares Hedge Replication ETF ProShares Trust | 71 | 3.1K $ | 0.01 % | as of Feb 28, 2026 · Original filing |
| 222 | Columbia Research Enhanced Small Cap ETF Columbia ETF Trust I | 68 | 3.4K $ | 0.11 % | as of Mar 31, 2026 · Original filing |
| 223 | Gotham Enhanced Return Fund FundVantage Trust | 59 | 3K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 224 | Gotham Neutral Fund FundVantage Trust | 58 | 2.9K $ | 0.00 % | as of Mar 31, 2026 · Original filing |
| 225 | Goldman Sachs MSCI World Private Equity Return Tracker ETF Goldman Sachs ETF Trust | 23 | 989.2 $ | 0.00 % | as of Feb 28, 2026 · Original filing |
| 226 | ProShares Russell 2000 Dynamic Buffer ETF ProShares Trust | 22 | 946.2 $ | 0.08 % | as of Feb 28, 2026 · Original filing |
| 227 | Russell 2000(R) 1.5x Strategy Fund Rydex Variable Trust | 18 | 907.9 $ | 0.03 % | as of Mar 31, 2026 · Original filing |
Institutional managers
189 managers declare this company to the SEC (Form 13F). These positions are not counted in the totals above: a manager and its own funds file separately.
| Manager | Shares | Value | |
|---|---|---|---|
| FMR LLC | 11,781,024 | 594.2M $ | as of Mar 31, 2026 |
| BlackRock, Inc. | 5,521,221 | 278.5M $ | as of Mar 31, 2026 |
| RTW INVESTMENTS, LP | 4,171,996 | 210.4M $ | as of Mar 31, 2026 |
| Fairmount Funds Management LLC | 4,018,101 | 202.7M $ | as of Mar 31, 2026 |
| PERCEPTIVE ADVISORS LLC | 3,783,225 | 190.8M $ | as of Mar 31, 2026 |
| Venrock Adviser, LLC | 3,685,448 | 185.9M $ | as of Mar 31, 2026 |
| Driehaus Capital Management LLC | 2,790,785 | 140.8M $ | as of Mar 31, 2026 |
| STATE STREET CORP | 2,607,031 | 131.5M $ | as of Mar 31, 2026 |
| Paradigm Biocapital Advisors LP | 1,957,266 | 98.7M $ | as of Mar 31, 2026 |
| Commodore Capital LP | 1,912,380 | 96.5M $ | as of Mar 31, 2026 |
| TCG Crossover Management, LLC | 1,900,582 | 95.9M $ | as of Mar 31, 2026 |
| TANG CAPITAL MANAGEMENT LLC | 1,892,200 | 95.4M $ | as of Mar 31, 2026 |
| WELLINGTON MANAGEMENT GROUP LLP | 1,824,811 | 92M $ | as of Mar 31, 2026 |
| Capital International Investors | 1,746,129 | 88.1M $ | as of Mar 31, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | 1,720,912 | 86.8M $ | as of Mar 31, 2026 |
| JANUS HENDERSON GROUP PLC | 1,656,164 | 83.6M $ | as of Mar 31, 2026 |
| RA CAPITAL MANAGEMENT, L.P. | 1,621,620 | 81.8M $ | as of Mar 31, 2026 |
| Remedium Capital Partners, LLC | 1,456,231 | 73.5M $ | as of Mar 31, 2026 |
| Affinity Asset Advisors, LLC | 1,279,134 | 64.5M $ | as of Mar 31, 2026 |
| BANK OF AMERICA CORP /DE/ | 1,228,093 | 61.9M $ | as of Mar 31, 2026 |
| BAKER BROS. ADVISORS LP | 1,000,000 | 50.4M $ | as of Mar 31, 2026 |
| BRAIDWELL LP | 932,823 | 47.1M $ | as of Mar 31, 2026 |
| FRANKLIN RESOURCES INC | 882,833 | 44.5M $ | as of Mar 31, 2026 |
| JPMORGAN CHASE & CO | 979,299 | 44.5M $ | as of Mar 31, 2026 |
| Caligan Partners LP | 878,127 | 44.3M $ | as of Mar 31, 2026 |